Percutaneous endoscopic gastrostomy sites infected by methicillin-resistant Staphylococcus aureus: impact on outcome

Journal of Clinical Gastroenterology
Inder MainieTony C K Tham

Abstract

The impact of methicillin-resistant Staphylococcus aureus (MRSA) colonization of percutaneous endoscopic gastrostomy (PEG) sites on morbidity and mortality is uncertain. We investigated the impact of known prior MRSA colonization on the incidence of symptomatic PEG site wound infection and mortality. Consecutive patients who had PEG tubes inserted recently at our hospital were identified. The presence or absence of MRSA colonization before PEG placement was noted. Patients were observed for wound infection, and swabs were taken from the site if there was clinical infection. Mortality within 30 days of PEG placement was determined. A total of 83 patients underwent PEG placement; 23 (28%) of these patients had known MRSA colonization before PEG placement. Of these, 13 (57%) developed symptomatic MRSA infection of the PEG site. The remaining 60 patients (72%) had no known prior MRSA colonization. In these patients, 9 (15%) developed symptomatic MRSA infection of the PEG site. The overall incidence of wound infection was 37% (31) of the total undergoing PEG placement, of whom 71% (22) had developed MRSA infection. The mortality of those with symptomatic MRSA infection of the PEG site was 9% (2/22), whereas the mortality from non-MR...Continue Reading

References

Jun 27, 1998·JAMA : the Journal of the American Medical Association·M D GrantJ A Brody
Jan 19, 2000·The American Journal of Gastroenterology·G AbuksisY Niv
Dec 12, 2001·Alimentary Pharmacology & Therapeutics·M HullC Settle
Jul 24, 2002·The American Journal of Gastroenterology·Kamran A ChaudharyWendell K Clarkston
Jan 23, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Susan S Huang, Richard Platt

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Citations

Oct 10, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Chiao-Hsiung ChuangBor-Shyang Sheu
Feb 5, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lona ModySarah L Krein
Jan 31, 2012·Infectious Disease Clinics of North America·Christopher J Crnich, Paul Drinka
Jul 3, 2013·British Journal of Community Nursing·Valerie Edwards-Jones, Anne Leahy-Gilmartin

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