Percutaneous endovascular tissue sampling of endoluminal tumors using directional atherectomy

European Radiology
Alexander MassmannPeter Fries

Abstract

To evaluate technical feasibility and safety of endovascular tumor specimen sampling using an escalating endovascular biopsy strategy using a directional atherectomy device compared with forceps biopsy and catheter aspiration. Between 2013 and 2017, a cohort of ten consecutive patients (6 male; median age 56, range 39-73 years) was referred for sampling of endovascular masses. Localizations included the abdominal aorta (n = 4), left brachiocephalic vein (n = 2), inferior vena cava (n = 1), and left pulmonary artery (n = 3). For each individual mass, all three endovascular tissue sampling approaches were applied including catheter-based aspiration, straight two-jaw biopsy forceps, and directional atherectomy during a single session. Aspiration and forceps biopsy did not provide sufficient material for histological analyses. In contrast, technical success for endovascular tumor sampling using directional atherectomy was 100%. After two atherectomy passages, sufficient material was available for each vessel region allowing histologic diagnosis, which revealed sarcoma and chronic inflammation for masses in the aorta, angiosarcoma for brachiocephalic vein, hepatocellular carcinoma for inferior vena cava, and angiosarcoma for pulmona...Continue Reading

References

Nov 1, 1989·Cardiovascular and Interventional Radiology·F CastanedaK Amplatz
Sep 1, 1996·AJR. American Journal of Roentgenology·P A WinchesterT A Sos
Apr 24, 2001·The American Journal of Gastroenterology·D KaufmanS K Dutta
Mar 1, 2012·Cardiovascular and Interventional Radiology·Alexander MassmannArno Buecker
Sep 28, 2016·Cardiovascular and Interventional Radiology·J A GuirolaM A De Gregorio
Feb 9, 2017·Journal of Medical Imaging and Radiation Oncology·Julian Maingard, Mark Brooks

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Citations

Aug 22, 2021·Heart, Lung & Circulation·Jifeng LiYuan-Hua Yang

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