PMID: 16628281Apr 22, 2006Paper

Percutaneous ethanol injection for the treatment of thyroid nodules

Arquivos brasileiros de endocrinologia e metabologia
Daysi M de Alcântara-JonesMarize Carvalho Passos

Abstract

To verify the effectiveness of percutaneous ethanol injection (PEI) in the treatment of thyroid nodules (TN), we analyzed 86 TN from 77 patients before and after one or two sessions of PEI. The medians of the initial and final volumes were: 3.5 mL (range 0.3-82.7) and 1.8 mL (range 0-29.4). Seven percent of the nodules disappeared and the mean nodule size reduction was 52.6% (p< 0.0001). After ethanol injection, the median volume reduction was: 37.3% (range -39.0-82.6) for solid; 53.5% (14.6-88.0) for mostly solid; 58.0% (21.0-64.5) for mixed; 71.0% (18.8-100.0) for mostly cystic and 90.0% (45.9-100.0) for cystic lesions. Furthermore, we compared the variation of the greatest diameter of TN, without any treatment and after PEI, and found this difference statistically significant (p< 0.00001). Pain was the most common complication, although this was mostly described as moderate (27.6%). We conclude that PEI is an efficient and safe treatment option for benign TN.

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Citations

Jan 30, 2015·Arquivos brasileiros de endocrinologia e metabologia·Camila Luhm Silva PerezGisah Amaral de Carvalho
Feb 26, 2016·Archives of Endocrinology and Metabolism·Mari Cassol FerreiraAna Carolina Cadore
May 4, 2021·Archives of Endocrinology and Metabolism·Daysi Maria de Alcântara-JonesLuis Fernando Fernandes Adan

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