Percutaneous ethanol injection versus conservative treatment for benign cystic and mixed thyroid nodules

Archives of Endocrinology and Metabolism
Mari Cassol FerreiraAna Carolina Cadore

Abstract

To evaluate the efficacy and safety of percutaneous ethanol injection (PEI) in reducing the volume of cystic and mixed thyroid nodules. A total of 36 patients with nodules treated with PEI and 13 individuals who declined PEI and were followed clinically or received other non surgical treatment (control group). Assessments were performed at baseline (immediately before treatment in the PEI group or evaluation of the nodule on ultrasonography in the control group) at short-term (on average 30 days after the last injection in the PEI group), and long-term (on average 14 months after baseline in the PEI group or 26 months after baseline in the control group). In the PEI group, the mean baseline volume of 10.4 ± 9.8 cm3 reduced at short-term follow-up to 2.9 ± 3.1 cm3 (67.7 ± 19.9%, p < 0.001) and at long-term follow-up to 2.0 ± 2.5 cm3 (78.2 ± 19.5%, p < 0.01 versus baseline and p = 0.009 versus short-term follow-up). Both types of nodules showed similar degrees of reduction. In the control group, mean volume was 5.8 ± 3.4 cm3 at baseline and 6.2 ± 3.0 cm3 at long-term follow-up (p = 0.507). Compared with the control group, the PEI group showed larger reduction (p < 0.001). PEI is effective in reducing the volume of cystic and mixe...Continue Reading

References

Jan 11, 2000·AJR. American Journal of Roentgenology·Y S ChoD C Suh
Jun 18, 2002·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Lech Pomorski, Magdalena Bartos
Sep 6, 2002·The Journal of Clinical Endocrinology and Metabolism·M Regina CastroJohn C Morris
Feb 4, 2003·Revista da Associação Médica Brasileira·Milena Braga-BasariaHans Graf
Feb 18, 2003·Endocrine Reviews·Laszlo HegedüsFinn N Bennedbaek
Apr 8, 2004·Thyroid : Official Journal of the American Thyroid Association·Rinaldo GuglielmiEnrico Papini
Apr 22, 2006·Arquivos brasileiros de endocrinologia e metabologia·Daysi M de Alcântara-JonesMarize Carvalho Passos
Feb 22, 2008·AJR. American Journal of Roentgenology·Luciano TarantinoUmberto Parmeggiani
Feb 29, 2008·The Oncologist·Meei J Yeung, Jonathan W Serpell
Mar 27, 2012·The Medical Clinics of North America·Geanina Popoveniuc, Jacqueline Jonklaas
Aug 21, 2013·The Journal of Clinical Endocrinology and Metabolism·Hossein GharibEnrico Papini
Jul 23, 2014·Best Practice & Research. Clinical Endocrinology & Metabolism·Enrico PapiniLaszlo Hegedus
Jan 30, 2015·Arquivos brasileiros de endocrinologia e metabologia·Camila Luhm Silva PerezGisah Amaral de Carvalho

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Citations

Apr 7, 2018·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Aysenur OzderyaSule Temizkan
Mar 27, 2019·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Enrico PapiniGiovanni Mauri
May 4, 2017·Case Reports in Endocrinology·Roberto CesareoAndrea Palermo
May 6, 2017·World Journal of Surgery·Yücel KorkusuzChristian Happel
May 26, 2017·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Alexander MaderChristian Happel
Mar 23, 2021·Endocrinología, Diabetes Y Nutrición·Agustín Ángel Merchante AlfaroCarlos Morillas Ariño
May 4, 2021·Archives of Endocrinology and Metabolism·Daysi Maria de Alcântara-JonesLuis Fernando Fernandes Adan

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