Percutaneous Impella RP use for refractory right heart failure in adolescents and young adults-A multicenter U.S. experience.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
Athar M QureshiBrian Morray

Abstract

To assess the outcomes of the use of the percutaneous Impella RP device (Abiomed, Danvers, MA) in adolescents and young adults. Results of the Impella RP device have been reported in adults, but a multicenter experience in adolescents and young adults has yet to be reported. Patients ≤21 years of age who underwent implantation of an Impella RP device for refractory right heart failure from June, 2016 to April, 2018 at nine U.S. Centers were included. A total of 12 adolescents, median age of 18 (14-21) years and median weight 74.4 (49-112.4) kg underwent Impella RP implantation (INTERMACS Profile 1 in nine and Profile 2 in three patients. The central venous pressure decreased from 20 (16-35) to 12 (7-17) mmHg, (p = .001). One patient was concomitantly supported with an intra-aortic balloon pump (IABP) and the rest with a percutaneous/surgically placed left ventricular assist device. There was one adverse event related to the Impella RP device (thrombosis requiring explant). The support duration was 6.5 days (4.8 hr-18.4 days) and survival to hospital discharge was 83%. At a median follow-up of 11 months (5 days-2.5 years), 8 of 12 (67%) patients are alive. In this multicenter experience, the Impella RP device was found to be eff...Continue Reading

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Citations

Jun 23, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Nikoloz ShekiladzeWissam A Jaber
Aug 17, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·James A Goldstein, Ivan Hanson
Dec 22, 2020·Journal of Cardiothoracic and Vascular Anesthesia·Luca ApruzziDomenico Baccellieri

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