Percutaneous pharmacomechanical thrombectomy offers lower risk of post-thrombotic syndrome than catheter-directed thrombolysis in patients with acute deep vein thrombosis of the lower limb

Annals of Vascular Surgery
Chun-Yang HuangChiao-Po Hsu

Abstract

Despite optimal anticoagulant therapy, patients with proximal deep vein thrombosis (DVT) will often develop post-thrombotic syndrome (PTS). Early thromboreduction can potentially decrease the risk of PTS by restoring venous patency and preserving valvular function. This study was undertaken to compare the efficacy and treatment outcomes of patients with acute proximal DVT of the lower limb who underwent either catheter-directed thrombolysis (CDT) or percutaneous pharmacomechanical thrombectomy (PMT). Thirty-nine patients with acute proximal DVT of the lower limb who were diagnosed by Wells' Score, PMT or CDT was chosen depending on the patient. They underwent early thromboreduction, and 3 died postoperatively in less than 12 months, while 2 were removed for not following-up. Thirty-four patients, 16 in PMT and 18 in CDT, were followed up for more than 1 year. Venous Registry Index (VRI) was used to evaluate the postprocedural patency, while PTS was assessed using the Villalta scale. The technical success was 100% in both the groups, without any 30-day mortality. VRI changed from 13.1 ± 4.3 preoperatively to 2.4 ± 1.5 postoperatively in the PMT group, and from 11.8 ± 2.4 to 3.6 ± 2.2 in the CDT group. Thrombolysis rate was 81.5 ...Continue Reading

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Citations

Nov 17, 2015·Expert Review of Cardiovascular Therapy·Aaron Liew, James Douketis
Nov 30, 2019·International Angiology : a Journal of the International Union of Angiology·João DinizArmando Mansilha
Aug 24, 2016·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Bin YangRan-Ran Meng
Feb 28, 2019·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Tao TangYongming Lu
Jul 15, 2020·Journal of Cardiovascular Translational Research·Song JinhuaShi Wanyin
Mar 22, 2021·Revue des maladies respiratoires·G PernodUNKNOWN Groupe de travail recommandations de bonne pratique pour la prise en charge de la MVTE
Apr 6, 2021·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Guan Qiang LiXi Cheng Zhang
Jul 16, 2020·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Anna L PounceyStephen A Black

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