Percutaneous radiofrequency ablation therapy of hepatocellular carcinoma using multitined expandable electrodes: comparison of subcapsular and nonsubcapsular tumors
Abstract
Our objective was to compare the prognosis of subcapsular and nonsubcapsular hepatocellular carcinoma after percutaneous radiofrequency ablation using multitined expandable electrodes. Some controversies exist about the clinical usefulness of percutaneous radiofrequency ablation of subcapsular hepatocellular carcinoma. Twenty-eight patients underwent percutaneous radiofrequency ablation of 43 hepatocellular carcinomas using multitined expandable electrodes. Twelve tumors were subcapsular and 31 were nonsubcapsular. We attempted to use normal liver as a pathway to the tumor when possible. Tumor size ranged from 1.0 to 4.2 cm (mean, 1.8 cm). Median follow-up was 16 months. Initial ablation was considered to have been complete when no enhancement was seen in the region of the ablated lesion on 1-month follow-up CT or on follow-up CT performed immediately after repeated ablation. Initial complete ablation and local tumor progression rates were compared between subcapsular and nonsubcapsular tumors. Eleven patients had subcapsular tumors (group 1), whereas the other 17 patients did not have subcapsular tumors (group 2). Major complication and mortality rates were compared between the two groups. No significant differences in initial...Continue Reading
References
Citations
Related Concepts
Related Feeds
Carcinoma, Hepatocellular
Hepatocellular Carcinoma is a malignant cancer in liver epithelial cells. Discover the latest research on Hepatocellular Carcinoma here.