PMID: 15235238Jul 6, 2004Paper

Percutaneous sclerotherapy of renal cysts with a beta-emitting radionuclide, holmium-166-chitosan complex

Korean Journal of Radiology : Official Journal of the Korean Radiological Society
Joo Hee KimSung Joon Hong

Abstract

To evaluate the usefulness of a beta-emitting radionuclide (holmium-166-chitosan complex) as a sclerosing agent for the treatment of renal cysts. Using 10-30 mCi of holmium-166-chitosan complex, 20 renal cysts in 17 patients (14 male and 3 female patients, ranging in age from 47 to 82 years) were treated by percutaneous sclerotherapy under ultrasonographic guidance. The volume of the cysts before and after the sclerotherapy and the percentage change in volume were calculated in order to evaluate the response to therapy, which was classified as either complete regression (invisible), nearly complete regression (< 15 volume% of initial volume), partial regression (15-50 volume%) or no regression (> 50 volume%). The follow-up period ranged from 6 to 36 months (mean 28 months). Eighteen cysts (90%) regressed completely (n=11, 55%) or near-completely (n=7, 35%). Partial regression was obtained in one patient (5%) and there was no regression in one patient (5%). No significant complications were encountered. The holmium-166-chitosan complex seems to be useful as a new painless sclerosing agent for the treatment of renal cysts with no significant complications.

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Citations

Oct 5, 2007·Cardiovascular and Interventional Radiology·Se Hwan KwonHo Chul Park
Oct 22, 2008·Journal of Endourology·Koo Han YooSeung Hyun Jeon
Nov 28, 2012·Journal of Vascular and Interventional Radiology : JVIR·Long LiXin-Qiao Zeng
Mar 15, 2012·BJU International·Andreas SkolarikosJean J M C H de la Rosette
May 24, 2018·Journal of Microencapsulation·Mariangela de Burgos M de AzevedoLjubica Tasic
Dec 12, 2007·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Hulusi EgilmezOrhan Solak
Jul 2, 2009·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·See Hyung KimJeong Yeon Cho
Nov 28, 2013·Journal of Korean Neurosurgical Society·Eun Jin HaGi Jeong Cheon
Oct 30, 2019·EJNMMI Radiopharmacy and Chemistry·Nienke J M KlaassenJ Frank W Nijsen

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