Percutaneous septal ablation for hypertrophic cardiomyopathy and mid-ventricular obstruction

European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology
H Seggewiss, L Faber

Abstract

Percutaneous transluminal septal myocardial ablation by alcohol-induced septal branch occlusion is a new treatment option in symptomatic patients with hypertrophic cardiomyopathy and subaortic, SAM-associated obstruction. We report on a patient with mid-ventricular obstruction and echocardiographic-guided reduction of septal hypertrophy. A 52-year-old woman with NYHA class III and recurrent exercise-induced syncope suffered from hypertrophic cardiomyopathy with mid-ventricular obstruction. She had a systolic gradient of 71 mmHg at rest and 153 mmHg post-extrasystole, and diastolic inflow gradient of 20 mmHg. Echo-guided percutaneous transluminal septal myocardial ablation with occlusion of the fourth septal branch resulted in acute reduction and final elimination of systolic, as well as diastolic resting and provocable gradients. Complications were not seen. At 3 months' follow-up the patient was asymptomatic and without further syncopes. Echocardiographic-guided percutaneous transluminal septal myocardial ablation is able to reduce gradients in hypertrophic cardiomyopathy and mid-ventricular obstruction with consecutive improvement of symptoms.

Citations

Aug 16, 2016·International Journal of Cardiology·M Fuad JanA Jamil Tajik
Dec 9, 2009·Echocardiography·Ajay ShahMark V Sherrid
Dec 24, 2005·The International Journal of Cardiovascular Imaging·I TengizU O Türk
Dec 1, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Angelos G Rigopoulos, Hubert Seggewiss
Mar 12, 2019·Deutsches Ärzteblatt International·Angelika BatznerHubert Seggewiß

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