Percutaneous transthoracic needle biopsy for pulmonary nodules: a retrospective study of a comparison between C-arm cone-beam computed tomography and conventional computed tomography guidance

Polish journal of radiology
Surasit Akkakrisee, Keerati Hongsakul

Abstract

To evaluate the safety and diagnostic performance of pulmonary nodule biopsies using cone-beam computed tomography (CBCT) guidance compared with conventional CT (CCT) guidance. Patients who had pulmonary nodules and underwent a transthoracic needle biopsy at the interventional unit from January 1, 2013 to June 30, 2018 were enrolled. CBCT with XperGuide software was used to biopsy 100 nodules, and CCT guidance was used to biopsy 266 nodules. The two techniques were compared in terms of radiation exposure, complications, and diagnostic accuracy. The p values of less than 0.05 were considered statistically significant. The characteristics of the nodules were similar between CBCT and CCT guidance. The median radiation doses were not significantly different between the two groups (5.6 mGy vs. 5.4 mGy; p = 0.78). All minor, major, and overall complications were insignificant (25% vs. 24.4%, 3% vs. 4.9% and 28% vs. 29.3%, respectively). Although CBCT guidance showed higher sensitivity and accuracy than CCT guidance (93.3% vs. 84.1% and 95.0% vs. 89.9%), both techniques had similar specificity (100% vs. 100%) in the diagnosis of malignancy. CBCT guidance in pulmonary nodule biopsy provided higher diagnostic sensitivity and accuracy th...Continue Reading

Methods Mentioned

BETA
biopsy
imaging techniques
X-ray
biopsies

Software Mentioned

R
XperGuide
XperCT
MedCalc

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