Percutaneous vertebroplasty is not a risk factor for new osteoporotic compression fractures: results from VERTOS II.

AJNR. American Journal of Neuroradiology
Caroline A KlazenHarald J J Verhaar

Abstract

PV is increasingly used as treatment for osteoporotic VCFs. However, controversy exists as to whether PV increases the risk for new VCFs during follow-up. The purpose of our research was to assess the incidence of new VCFs in patients with acute VCFs randomized to PV and conservative therapy. VERTOS II is a prospective multicenter randomized controlled trial comparing PV with conservative therapy in 202 patients. Incidence, distribution, and timing of new VCFs during follow-up were assessed from spine radiographs. In addition, further height loss during follow-up of treated VCFs was measured. After a mean follow-up of 11.4 months (median, 12.0; range, 1-24 months), 18 new VCFs occurred in 15 of 91 patients after PV and 30 new VCFs in 21 of 85 patients after conservative therapy. This difference was not significant (P = .44). There was no higher fracture risk for adjacent-versus-distant vertebrae. Mean time to new VCF was 16.2 months after PV and 17.8 months after conservative treatment (logrank, P = .45). The baseline number of VCFs was the only risk factor for occurrence (OR, 1.43; 95% CI, 1.05-1.95) and number (P = .01) of new VCFs. After conservative therapy, further height loss of treated vertebrae occurred more frequently ...Continue Reading

Associated Clinical Trials

Oct 4, 2005·Clinical Research Office Imaging Division

References

Aug 1, 1992·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
Feb 1, 1992·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·C CooperL J Melton
Aug 1, 1991·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
Mar 1, 1991·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·R EastellL J Melton
Sep 1, 1993·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·H K GenantM C Nevitt
Nov 5, 2003·Radiology·Gamal BaroudThomas Steffen
Jan 18, 2006·Journal of Vascular and Interventional Radiology : JVIR·Maurits H J VoormolenLeo E H Lampmann
Mar 28, 2006·Cardiovascular and Interventional Radiology·Atsushi KomemushiSatoshi Sawada
Sep 20, 2006·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·O Johnell, J A Kanis
Jul 2, 2008·Cardiovascular and Interventional Radiology·Johannes HierholzerRudolf Schulz
Sep 18, 2008·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A S MudanoK G Saag
Aug 29, 2009·AJNR. American Journal of Neuroradiology·F Al-AliK Luke

❮ Previous
Next ❯

Citations

Dec 16, 2011·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Michael KinzlDieter H Pahr
May 17, 2013·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Jan Philipp KolbWolfgang Lehmann
Jul 25, 2013·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Tobias L SchulteWerner Schmoelz
Nov 23, 2013·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·O LamyB Aubry-Rozier
Nov 30, 2013·Archives of Orthopaedic and Trauma Surgery·Xiaodong YiHong Li
May 23, 2012·Cardiovascular and Interventional Radiology·Thijs A J Urlings, Edwin van der Linden
Jan 6, 2016·The British Journal of Radiology·Mario MutoLuigi Manfrè
May 6, 2014·Neuroimaging Clinics of North America·Sudhir Kathuria
Nov 6, 2012·Journal of the American Medical Directors Association·Yi-Wen TsaiLiang-Kung Chen
Oct 23, 2012·Clinical Biomechanics·Michael KinzlDieter H Pahr
Aug 28, 2012·Journal of Vascular and Interventional Radiology : JVIR·Wen-Gui LiuGao-Jun Teng
Aug 28, 2012·Journal of Vascular and Interventional Radiology : JVIR·Peter L Munk
Oct 25, 2011·Journal of Vascular and Interventional Radiology : JVIR·Giovanni Carlo AnselmettiDaniele Regge
Feb 22, 2013·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Angeles Martinez-FerrerPilar Peris
Apr 20, 2012·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Jordi BlascoPilar Peris
Oct 3, 2015·European Radiology·Frédéric ClarençonJacques Chiras
Jun 15, 2015·The Spine Journal : Official Journal of the North American Spine Society·Nathan EvaniewGordon Guyatt
Feb 11, 2014·Journal of the Mechanical Behavior of Biomedical Materials·Alejandro LópezBenedikt Helgason
Aug 10, 2011·Orvosi hetilap·Péter Pál VargaÁron Lazáry
May 8, 2014·European Journal of Radiology·M MutoV Pereira
Oct 3, 2012·Diagnostic and Interventional Imaging·A IannessiJ Sedat
Jun 29, 2014·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Ying-Ze ZhangYong Shen
Nov 9, 2014·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·F BorgströmK Akesson
Jan 21, 2017·Cardiovascular and Interventional Radiology·Georgia TsoumakidouAfshin Gangi
May 28, 2015·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Gianluigi GuarnieriMario Muto
Apr 5, 2018·The Cochrane Database of Systematic Reviews·Rachelle BuchbinderDavid F Kallmes
Sep 1, 2017·Cardiovascular and Interventional Radiology·Dimitrios K FilippiadisAlexis Kelekis
Apr 27, 2016·Asian Spine Journal·Amer SebaalyRami El Rachkidi
Sep 3, 2017·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Qirui DingLipeng Yu

❮ Previous
Next ❯

Related Concepts

Related Feeds

22q11 Deletion Syndrome

22q11.2 deletion syndrome, also known as DiGeorge syndrome, is a congenital disorder caused by a partial deletion of chromosome 22. Symptoms include heart defects, poor immune system function, a cleft palate, complications related to low levels of calcium in the blood, and delayed development. Discover the latest research on this disease here.

Related Papers

AJNR. American Journal of Neuroradiology
F Al-AliK Luke
Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
Howard LevyVin Tangpricha
© 2021 Meta ULC. All rights reserved