Perforation of the nasal septum in patients with renal failure

The Laryngoscope
D Adler, E Ritz

Abstract

Spontaneous perforation of the nasal septum was observed in 8 out of 104 patients (74 on maintenance hemodialysis; 30 after cadaveric renal transplantation). All patients showed a round or oval defect of the non-osseous septum, which was accompanied by marked atrophic rhinitis. Epistaxis was common in uremic patients in general and was also present in 5 patients with septal perforation, but otherwise the defect was hardly associated with any symptoms. Various factors may play a role in the pathogenesis of this lesion; local trauma from nasal catheters postoperatively; impaired mucosa cell proliferation; disturbed innervation of the vessels in the nasal septum due to polyneuropathy of the autonomous nervous system; ischemia secondary to arteriolar narrowing.

Citations

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Mar 25, 1999·Revista clínica española·E Calvo BoizasF Gómez Toranzo
Jun 13, 2001·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·F Alawi, P D Freedman
Jul 15, 2015·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Cuneyt KucurFatih Oghan
Dec 17, 2002·La Revue de médecine interne·S VignesJ C Piette

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