Performance analysis of a new computer aided detection system for identifying lung nodules on chest radiographs

Medical Image Analysis
Russell C HardieAdam Rogers

Abstract

A new computer aided detection (CAD) system is presented for the detection of pulmonary nodules on chest radiographs. Here, we present the details of the proposed algorithm and provide a performance analysis using a publicly available database to serve as a benchmark for future research efforts. All aspects of algorithm training were done using an independent dataset containing 167 chest radiographs with a total of 181 lung nodules. The publicly available test set was created by the Standard Digital Image Database Project Team of the Scientific Committee of the Japanese Society of Radiological Technology (JRST). The JRST dataset used here is comprised of 154 chest radiographs containing one radiologist confirmed nodule each (100 malignant cases, 54 benign cases). The CAD system uses an active shape model for anatomical segmentation. This is followed by a new weighted-multiscale convergence-index nodule candidate detector. A novel candidate segmentation algorithm is proposed that uses an adaptive distance-based threshold. A set of 114 features is computed for each candidate. A Fisher linear discriminant (FLD) classifier is used on a subset of 46 features to produce the final detections. Our results indicate that the system is ab...Continue Reading

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Citations

Apr 26, 2011·International Journal of Computer Assisted Radiology and Surgery·Michael SchwierHeinz-Otto Peitgen
Jun 12, 2012·International Journal of Computer Assisted Radiology and Surgery·Atsushi Teramoto, Hiroshi Fujita
Apr 7, 2012·International Journal of Biomedical Imaging·Kenji Suzuki
Feb 23, 2013·International Journal of Biomedical Imaging·Ayman El-BazBehnoush Abdollahi
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Oct 4, 2011·Academic Radiology·Diederick W De BooCornelia M Schaefer-Prokop
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Nov 30, 2012·IEEE Transactions on Bio-medical Engineering·Sheng Chen, Kenji Suzuki
Jul 22, 2011·IEEE Transactions on Bio-medical Engineering·Seongjin ParkYeong-Gil Shin
Mar 30, 2010·Medical Image Analysis·Temesguen MessaySteven K Rogers
Feb 7, 2017·IEEE Journal of Biomedical and Health Informatics·Xuechen LiSuhuai Luo
Mar 1, 2018·Journal of Medical Imaging·Barath Narayanan NarayananTemesguen Messay Kebede
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Jul 4, 2016·Journal of Healthcare Engineering·Juan Manuel Carrillo-de-GeaJosé Luis Hernández-Hernández
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Jan 13, 2021·Cold Spring Harbor Perspectives in Medicine·Ilke TunaliMatthew B Schabath
Sep 29, 2020··Kenneth J. Barnard, Kenneth J. Barnard

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