Performance and outcome of pelvic exenteration for gynecologic malignancies: A population-based study

Gynecologic Oncology
Koji MatsuoJason D Wright

Abstract

To examine changes in performance and outcomes of pelvic exenteration for gynecologic malignancies. This is a population-based retrospective study examining the Nationwide Inpatient Sample between 2001 and 2015. Women with cervical, uterine, vaginal, and vulvar malignancies who underwent pelvic exenteration were examined. Comorbidity, perioperative complications, total charges, length of stay, and mortality were assessed. There were 2647 cases included. Cervical cancer was the most common malignancy (45.1%), followed by vaginal cancer (27.6%). 26.9% of women had a Charlson Comorbidity Index ≥3, which significantly increased from 23.3% in 2001-2005 to 33.3% in 2011-2015 (42.9% relative increase, P < 0.001). Obese women undergoing exenteration increased significantly from 4.5% in 2001-2005 to 19.4% in 2011-2015 (3.3-fold relative increase, P < 0.001). The perioperative complication rate was 68.1%, including 38.7% with multiple complications. The mortality rate was 1.9%. The number of women with multiple perioperative complications increased from 29.4% in 2001-2005 to 52.8% in 2011-2015 (78.6% relative increase, P < 0.001). More recent year of surgery, obesity, higher comorbidity, higher household income, surgery at large bedsize ...Continue Reading

Citations

Feb 23, 2020·BJOG : an International Journal of Obstetrics and Gynaecology·R S MandelbaumK Matsuo
Sep 4, 2020·World Journal of Surgical Oncology·Agnieszka LewandowskaLukasz Wicherek
Oct 27, 2020·Annals of Surgical Oncology·Hari T VigneswaranMichael R Abern
Jan 27, 2021·Journal of Minimally Invasive Gynecology·Koji MatsuoLynda D Roman
May 8, 2021·The British Journal of Radiology·Pamela Ines Causa AndrieuSoleen Ghafoor

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