Performance Evaluation of Biozentech Malaria Scanner in Plasmodium knowlesi and P. falciparum as a New Diagnostic Tool.

The Korean Journal of Parasitology
Egy Rahman FirdausEun-Taek Han

Abstract

The computer vision diagnostic approach currently generates several malaria diagnostic tools. It enhances the accessible and straightforward diagnostics that necessary for clinics and health centers in malaria-endemic areas. A new computer malaria diagnostics tool called the malaria scanner was used to investigate living malaria parasites with easy sample preparation, fast and user-friendly. The cultured Plasmodium parasites were used to confirm the sensitivity of this technique then compared to fluorescence-activated cell sorting (FACS) analysis and light microscopic examination. The measured percentage of parasitemia by the malaria scanner revealed higher precision than microscopy and was similar to FACS. The coefficients of variation of this technique were 1.2-6.7% for Plasmodium knowlesi and 0.3-4.8% for P. falciparum. It allowed determining parasitemia levels of 0.1% or higher, with coefficient of variation smaller than 10%. In terms of the precision range of parasitemia, both high and low ranges showed similar precision results. Pearson's correlation test was used to evaluate the correlation data coming from all methods. A strong correlation of measured parasitemia (r2=0.99, P<0.05) was observed between each method. The p...Continue Reading

References

Jul 1, 1981·The American Journal of Tropical Medicine and Hygiene·H C SpencerJ C Skinner
Jan 5, 2006·Applied and Environmental Microbiology·Willm Martens-Habbena, Henrik Sass
Dec 7, 2006·Scandinavian Journal of Infectious Diseases·Lothar WieseJørgen A L Kurtzhals
Dec 8, 2006·Sexually Transmitted Infections·R W PeelingA Ronald
Sep 23, 2008·Molecular Diagnosis & Therapy·Rachel N BronzanS Patrick Kachur
Feb 8, 2011·Journal of Immunological Methods·Brian T Grimberg
May 9, 2012·Malaria Journal·William R PrescottChristopher Schwabe
Dec 26, 2012·Proceedings of the National Academy of Sciences of the United States of America·Robert W MoonMichael J Blackman
Apr 5, 2013·Journal of Microscopy·J P VinkG DE Haan
Apr 5, 2013·Clinical Microbiology Reviews·Balbir Singh, Cyrus Daneshvar
Sep 4, 2014·Frontiers in Public Health·Ranjan Ramasamy
Jun 11, 2015·PLoS Neglected Tropical Diseases·David M PigottSimon I Hay
Feb 13, 2016·Journal of Clinical Microbiology·Todd A. CuttsSteven S Theriault
Dec 16, 2016·Journal of Clinical Microbiology·Yochay EshelSeth J Salpeter
Sep 5, 2017·Bulletin of the World Health Organization·Cara S KosackPaul R Klatser
Sep 8, 2017·Frontiers in Public Health·Joseph Joel PollakSeth J Salpeter
Oct 21, 2017·Blood·Patrick G Gallagher
Jul 20, 2019·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Myo Thura Zaw, Zaw Lin

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