Performance evaluation of polycrystalline HgI2 photoconductors for radiation therapy imaging.

Medical Physics
Qihua ZhaoJin Yamamoto

Abstract

Electronic portal imaging devices based on megavoltage (MV), active matrix, flat-panel imagers (AMFPIs) are presently regarded as the gold standard in portal imaging for external beam radiation therapy. These devices, employing indirect detection of incident radiation by means of a metal plate plus phosphor screen combination, offer a quantum efficiency of only approximately 2% at 6 MV, leading to a detective quantum efficiency (DQE) of only approximately 1%. In order to significantly improve the DQE performance of MV AMFPIs, a strategy based on the development of direct detection imagers incorporating thick films of polycrystalline mercuric iodide (HgI2) photoconductor was undertaken and is reported. Two MV AMFPI prototypes, one incorporating an approximately 300 microm thick HgI2 layer created through physical vapor deposition (PVD) and a second incorporating an approximately 460 microm thick HgI2 layer created through screen-printing of particle-in-binder (PIB) material, were quantitatively evaluated using a 6 MV photon beam. The reported measurements include empirical determination of x-ray sensitivity, lag, modulation transfer function (MTF), noise power spectrum, and DQE. For both prototypes, MTF and DQE results were foun...Continue Reading

References

Sep 1, 1978·International Journal of Radiation Oncology, Biology, Physics·R W ByhardtG Liermann
Oct 1, 1992·Physics in Medicine and Biology·D G LewisZ R Xiao
Jan 1, 1992·Medical Physics·A L BoyerJ Wong
Oct 1, 1996·International Journal of Radiation Oncology, Biology, Physics·L E AntonukY el-Mohri
Jun 1, 1997·Medical Physics·J P BissonnetteP Munro
Dec 12, 1997·Physics in Medicine and Biology·J R Symonds-TaylerP M Evans
Jul 3, 1998·Medical Physics·T FalcoB G Fallone
Oct 27, 1998·International Journal of Radiation Oncology, Biology, Physics·L E AntonukJ Yorkston
Jan 6, 1999·Medical Physics·M A Mosleh-ShiraziM Partridge
Feb 14, 2002·Physics in Medicine and Biology·Tsang CheungPeter K N Yu
Sep 24, 2002·International Journal of Radiation Oncology, Biology, Physics·Jon J KruseThomas M Pisansky
Dec 19, 2002·Journal of Medical Engineering & Technology·G QiS Samant
Feb 8, 2003·International Journal of Radiation Oncology, Biology, Physics·Ed J SeppiRick E Colbeth
Mar 2, 2005·International Journal of Radiation Oncology, Biology, Physics·Jean PouliotLynn Verhey
May 14, 2005·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Mark OldhamJohn W Wong
Nov 22, 2007·Physics in Medicine and Biology·P Rassiah-SzegediB Salter
Jan 1, 1992·IEEE Transactions on Medical Imaging·H FujitaA Ohtsuka

❮ Previous
Next ❯

Citations

Aug 6, 2011·Medical Physics·Jongduk Baek, Norbert J Pelc
Sep 16, 2016·Scientific Reports·O SemeniukA Reznik
May 31, 2017·Medical Physics·Marios MyronakisRoss I Berbeco
Jan 22, 2021·Advanced Materials·Yucheng LiuShengzhong Frank Liu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.