Performance of an automated computer-based scoring method to assess joint space narrowing in rheumatoid arthritis: a longitudinal study

Arthritis and Rheumatism
Axel FinckhJeffrey Duryea

Abstract

To compare the diagnostic performance of a computer-based method for measuring joint space width with the Sharp joint space narrowing (JSN) scoring method in patients with rheumatoid arthritis (RA). A random sample of patients with early RA, for whom sequential hand radiographs and Sharp scores were available, was selected from the National Data Bank for Rheumatic Diseases. Hand joint space width was measured using an automated, computer-based method in random order and with blinding for clinical information. We constructed a receiver operating characteristic curve and compared the diagnostic performance of the computer-based and Sharp methods based on the areas under the curve. One hundred twenty-nine patients with early RA who underwent serial radiography were included. Changes in the computer-based and Sharp methods were highly correlated (r = 0.75, P < 0.001). The computer-based method was significantly more discriminant than the Sharp JSN subscale. The area under the curve of the computer-based method was 0.96 (95% confidence interval [95% CI] 0.94, 0.99) compared with 0.93 (95% CI 0.89, 0.96) for the Sharp subscale (P = 0.024). At the most discriminant cutoff, specificity of the computer-based method was 88.4% compared wi...Continue Reading

References

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Citations

Apr 20, 2010·Rheumatology International·Alexander PfeilJoachim Böttcher
Dec 19, 2012·Joint, Bone, Spine : Revue Du Rhumatisme·Alexander PfeilJoachim Böttcher
May 22, 2009·European Journal of Radiology·Philipp PeloschekGeorg Langs
Mar 3, 2009·Annals of the New York Academy of Sciences·Olga KubassovaSøren Torp-Pedersen
Jan 1, 2009·IEEE Transactions on Medical Imaging·Georg LangsFranz Kainberger
May 9, 2015·Osteoarthritis and Cartilage·D J HunterG E Gold
Oct 20, 2010·Arthritis Care & Research·Gesa NeumannJeffrey Duryea
Mar 22, 2019·The British Journal of Educational Psychology·Henry Braun

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