Performance of lung ultrasound in the diagnosis of pediatric pneumonia in Mozambique and Pakistan.

Pediatric Pulmonology
Amy Sarah GinsburgGiovanni Volpicelli

Abstract

Improved pneumonia diagnostics are needed in low-resource settings (LRS); lung ultrasound (LUS) is a promising diagnostic technology for pneumonia. The objective was to compare LUS versus chest radiograph (CXR), and among LUS interpreters, to compare expert versus limited training with respect to interrater reliability. We conducted a prospective, observational study among children with World Health Organization (WHO) Integrated Management of Childhood Illness (IMCI) chest-indrawing pneumonia at two district hospitals in Mozambique and Pakistan, and assessed LUS and CXR examinations. The primary endpoint was interrater reliability between LUS and CXR interpreters for pneumonia diagnosis among children with WHO IMCI chest-indrawing pneumonia. Interrater reliability was excellent for expert LUS interpreters, but poor to moderate for expert CXR interpreters and onsite LUS interpreters with limited training. Among children with WHO IMCI chest-indrawing pneumonia, expert interpreters may achieve substantially higher interrater reliability for LUS compared to CXR, and LUS showed potential as a preferred reference standard. For point-of-care LUS to be successfully implemented for the diagnosis and management of pneumonia in LRS, the c...Continue Reading

References

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Citations

Feb 12, 2021·ERJ Open Research·Amy Sarah GinsburgGiovanni Volpicelli
Mar 20, 2021·Scientific Reports·Amy Sarah GinsburgGiovanni Volpicelli

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Methods Mentioned

BETA
bronchoalveolar lavage

Clinical Trials Mentioned

NCT03187067

Software Mentioned

R Foundation for Statistical Computing
R

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