Performance of posttransplant Model for End-Stage Liver Disease (MELD) and delta-MELD scores on short-term outcome after living donor liver transplantation

Transplantation Proceedings
J D KimD G Kim

Abstract

The performance of the Model for End-stage Liver Disease (MELD) and delta-MELD scores in predicting posttransplant survival has been variable and the results are conflicting, suggesting that posttransplantational factors are more important than pre- or peritransplantational factors in outcomes following liver transplantation (OLT). We assessed the value of posttransplant MELD and delta-MELD scores to predict short-term (90-day) posttransplant survival. We evaluated 279 consecutive patients undergoing living donor OLTs. The MELD scores were calculated serially from pretransplantation as well as 3, 7, and 14 days after transplantation. Twenty-seven (9.7%) among 279 patients died within 90 days after transplantation. Pretransplant MELD score was not associated with short-term posttransplant mortality. The area under the receiver operating characteristic (AUROC) curve in predicting 90-day mortality was 0.637 for posttransplant 3-day MELD, 0.746 for posttransplant 7-day MELD, and 0.859 for posttransplant 14-day MELD score (P = .047, <.001, and <.001, respectively); AUROC was 0.582, 0.646, and 0.784 for 3-day, 7-day, and 14-day delta-MELD scores (P = .235, .034, <.001, respectively). Upon multivariate analysis, posttransplant 14-day ...Continue Reading

References

May 4, 2005·Transplantation Proceedings·B Sánchez-PerezA De la Fuente
Jun 24, 2005·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Matthew JacobJan H P van der Meulen
Jun 27, 2006·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Evangelos CholongitasAndrew K Burroughs
Feb 28, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Patrick S KamathUNKNOWN Advanced Liver Disease Study Group

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Citations

Jun 21, 2016·Scandinavian Journal of Gastroenterology·Andreas A RostvedAllan Rasmussen
Sep 13, 2016·Osteoarthritis and Cartilage·F S XueC Sun
Jun 1, 2013·Hepatology International·Thomas Schiano
Feb 25, 2018·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Ujjwal Sonika Shalimar
Sep 30, 2009·The Mount Sinai Journal of Medicine, New York·Hui-Hui TanPaul Martin
May 10, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Y YangL Ma
Sep 29, 2017·European Journal of Gastroenterology & Hepatology·Talaat ZakareyaImam Waked
Aug 26, 2017·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Faiz Gani, Timothy M Pawlik
Sep 9, 2017·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Hui-Xian LiGui-Zhen Yang
Sep 19, 2017·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Fu-Shan XueGui-Zhen Yang
Nov 4, 2020·Langenbeck's Archives of Surgery·Hans-Christian PommergaardAllan Rasmussen

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