Performance of Prognostic Risk Scores in Chronic Heart Failure Patients Enrolled in the European Society of Cardiology Heart Failure Long-Term Registry

JACC. Heart Failure
Marco CanepaESC HF Long Term Registry Investigators

Abstract

This study compared the performance of major heart failure (HF) risk models in predicting mortality and examined their utilization using data from a contemporary multinational registry. Several prognostic risk scores have been developed for ambulatory HF patients, but their precision is still inadequate and their use limited. This registry enrolled patients with HF seen in participating European centers between May 2011 and April 2013. The following scores designed to estimate 1- to 2-year all-cause mortality were calculated in each participant: CHARM (Candesartan in Heart Failure-Assessment of Reduction in Mortality), GISSI-HF (Gruppo Italiano per lo Studio della Streptochinasi nell'Infarto Miocardico-Heart Failure), MAGGIC (Meta-analysis Global Group in Chronic Heart Failure), and SHFM (Seattle Heart Failure Model). Patients with hospitalized HF (n = 6,920) and ambulatory HF patients missing any variable needed to estimate each score (n = 3,267) were excluded, leaving a final sample of 6,161 patients. At 1-year follow-up, 5,653 of 6,161 patients (91.8%) were alive. The observed-to-predicted survival ratios (CHARM: 1.10, GISSI-HF: 1.08, MAGGIC: 1.03, and SHFM: 0.98) suggested some overestimation of mortality by all scores exce...Continue Reading

Citations

Jul 4, 2019·Circulation. Cardiovascular Quality and Outcomes·Ryhm RadjefDavid E Lanfear
Jan 23, 2020·Scandinavian Cardiovascular Journal : SCJ·Ismail Bolat, Murat Biteker
Apr 16, 2020·European Journal of Clinical Investigation·Hyun-Jin KimShung Chull Chae
Oct 28, 2019·European Journal of Heart Failure·Cristiana VitaleAndrew J Coats
Nov 14, 2019·European Journal of Heart Failure·Eric D AdlerAvi Yagil
Aug 3, 2020·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Scott C SilvestryWilliam G Cotts
Mar 7, 2019·American Journal of Therapeutics·Elena-Laura AntohiOvidiu Chioncel
Dec 31, 2019·European Heart Journal Supplements : Journal of the European Society of Cardiology·Cristiana Vitale, Loreena Hill
Apr 3, 2020·European Journal of Heart Failure·Chris J KapeliosUNKNOWN Heart Failure Long-Term Registry Investigators Group
Jan 21, 2021·Arquivos brasileiros de cardiologia·Fabiana G Marcondes-BragaNadine Clausell
May 2, 2021·ESC Heart Failure·Tauben AverbuchHarriette Gillian Christine Van Spall
Jun 6, 2021·Journal of Cardiac Failure·Laura P GelfmanNathan E Goldstein
Oct 4, 2021·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Fozia Zahir AhmedJoanne K Taylor

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