Abstract
There is a growing interest in ultrasound evaluation of bone status as an alternative to the measurement with dual X-ray absorptiometry (DXA), due to its low cost, portability, and nonionizing radiation. The aim of our study was to investigate the relation among DXA, QUS, clinical, anthropometric, and lifestyle factors, and to determine QUS cutoff values in order to discriminate fractures in patients referred to the Bone Metabolic Unit at an Endocrinology Service. We studied 300 patients (281 females and 19 males; age 58 +/- 11 years) referred for evaluation of osteoporosis. In all cases we determined basic anthropometric parameters, a clinical history including previous osteoporotic fractures and risk factors for osteoporosis, and QUS parameters in calcaneus (Hologic Sahara), and BMD in lumbar spine (LS) and femoral neck (FN), by DXA (Hologic QDR 1000). Using the WHO densitometric criteria, 37, 46.7, and 16.3% of our population were osteoporotic, osteopenic, and normal, respectively. A QUI T-score </=-1.5 SD provided a sensitivity of 68.9% and a specificity of 64.7% for osteoporotic fracture discrimination and a sensitivity of 64.9% and a specificity of 74.1% for osteoporosis defined by WHO criteria using DXA. In the logistic ...Continue Reading
References
Apr 1, 1990·The Journal of Clinical Endocrinology and Metabolism·E S OrwollT Mann
Mar 2, 1989·The New England Journal of Medicine·E SeemanG Jerums
Dec 1, 1985·Calcified Tissue International·M KleerekoperA M Parfitt
Jan 1, 1995·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C C GlüerH K Genant
Jan 1, 1993·Calcified Tissue International·C Cooper
Jan 1, 1993·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C G MillerG M Blake
Aug 24, 1996·Lancet·D HansP J Meunier
Feb 1, 1997·Bone·M N DiazA J Silman
Jan 1, 1997·Annals of Epidemiology·A Rosengren, L Wilhelmsen
Nov 3, 1998·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·P ThompsonR Oliver
May 26, 1999·Maturitas·P HadjiK D Schulz
Jun 15, 1999·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M B MikhailJ F Aloia
Aug 18, 1999·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C C Glüer, D Hans
Nov 5, 1999·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·K G FaulknerP Miller
Jan 7, 2000·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S M PluijmP Lips
Feb 9, 2000·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M L FrostI Fogelman
Aug 6, 2000·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M L FrostI Fogelman
May 17, 2001·Calcified Tissue International·J DamilakisN Gourtsoyiannis
Jul 11, 2001·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S L GreenspanUNKNOWN QUS-2 PMA Trials Group
Jul 12, 2001·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M L FrostI Fogelman
Aug 31, 2001·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·K Brooke-WavellY Yamada
Jul 11, 2002·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M SosaUNKNOWN GIUMO Study Group
Citations
Jul 9, 2004·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Faidon MagkosLabros S Sidossis
Jul 11, 2006·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·W LiuG-J Zhu
Jan 20, 2007·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A Díez-PérezUNKNOWN Ecografía Osea en Atención Primaria study investigators
Nov 8, 2008·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·T YamamotoR Teshima
Apr 21, 2007·Journal of Bone and Mineral Metabolism·Ayfer GemalmazOkay Basak
Jul 1, 2009·Indian Journal of Clinical Biochemistry : IJCB·S AgrawalC Raghunandan
Aug 9, 2006·Menopause : the Journal of the North American Menopause Society·Atsushi TashiroYutaka Takeuchi
Mar 11, 2006·BMC Musculoskeletal Disorders·Nan-Ping YangPesus Chou
Apr 7, 2004·Journal of Physiological Anthropology and Applied Human Science·Fumihiro OmasuYoshibumi Nakahara
Jul 14, 2009·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·George TrovasNikos Papaioanou
Apr 30, 2008·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Marc-Antoine KriegDidier Hans
Aug 26, 2006·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·W LiuG J Zhu
Jul 4, 2006·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Fernando MarínMiguel Delgado-Rodríguez
Jul 13, 2004·The American Journal of Cardiology·Tiziana MontalciniArturo Pujia
Oct 26, 2011·Medicina clínica·Antonia García-MartínManuel Muñoz-Torres
Nov 30, 2005·European Journal of Internal Medicine·M SosaUNKNOWN GIUMO Study Group
Apr 29, 2006·Bone·A StewartD M Reid
Jul 10, 2007·Journal of the American Pharmacists Association : JAPhA·Yifei LiuXiaoyun Pan
Sep 30, 2016·Acta orthopaedica et traumatologica turcica·Fatih CesmeAydan Oral
Jul 26, 2005·Joint, Bone, Spine : Revue Du Rhumatisme·Daniel WendlingFabrice Michel
Jul 17, 2004·Calcified Tissue International·J L HernándezUNKNOWN ECOSAP study investigators