Performance of the EQ-5D in patients with irritable bowel syndrome

Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Donald M BushnellAndrea Bracco

Abstract

The EQ-5D is a standardized, nondisease-specific instrument for evaluating patients' preference-based valuations of health-related quality of life (HRQoL). This study's purpose was to determine the psychometric properties of EQ-5D in patients with irritable bowel syndrome (IBS). Data from four European IBS studies were assessed: UK (n = 161 and n = 297), Spain (n = 503), and Germany (n = 100). The EQ-5D is a five-item health state descriptive system used to develop health states (EQ-5D(INDEX)) and a visual analog scale (VAS) (0-100 from worst to best imaginable health state, EQ-5D(VAS)). Measures used with the EQ-5D included the SF-36, Irritable Bowel Syndrome--Quality of Life (IBS-QOL), and both subjective and clinical global assessments of IBS. Convergent validity was assessed using SF-36 and IBS-QOL data, discriminant validity using global ratings of IBS severity, and responsiveness by subjective and physician assessment of condition. Moderate-to-high associations (r >or= 0.33) were seen between the EQ-5D(VAS) and the SF-36 and IBS-QOL subscales. Mean response scores to EQ-5D(INDEX) dimensions and the EQ-5D(VAS) score were significantly better for control patients than for patients with IBS (all P < 0.01). The EQ-5D(VAS) was...Continue Reading

References

Oct 16, 1996·JAMA : the Journal of the American Medical Association·M C WeinsteinL B Russell
Feb 1, 1997·Alimentary Pharmacology & Therapeutics·M Camilleri, M G Choi
Jun 1, 1997·Gastroenterology·D A DrossmanM Camilleri
Jun 6, 1996·Health Policy·R Brooks
Jun 16, 2001·The New England Journal of Medicine·B J Horwitz, R S Fisher
Jul 18, 2001·PharmacoEconomics·R Lea, P J Whorwell
Aug 17, 2001·European Journal of Gastroenterology & Hepatology·W G ThompsonA Caballero-Plasencia
Jul 13, 2002·Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society·Margaret HeitkemperEleanor Bond
Nov 28, 2002·Gastroenterology·Douglas A DrossmanWilliam E Whitehead
Jul 9, 2003·Current Treatment Options in Gastroenterology·Kevin W. Olden
Sep 13, 2003·British Journal of Clinical Pharmacology·Nicholas J Talley

❮ Previous
Next ❯

Citations

Sep 21, 2013·Health and Quality of Life Outcomes·Mariana BrussoniKerry Walker
Feb 7, 2014·International Journal of Technology Assessment in Health Care·David TordrupPanos Kanavos
Nov 28, 2012·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Leyla MohseninejadErik Buskens
Jun 18, 2015·Journal of Clinical Gastroenterology·Sveta S OzaDaniel A Leffler
Jun 19, 2010·Journal of Advanced Nursing·Kristina LämåsCatrine Jacobsson
Sep 10, 2014·Alimentary Pharmacology & Therapeutics·C CanavanT Card
Jun 5, 2015·PharmacoEconomics·Nalin PayakachatJ Mick Tilford
Sep 25, 2014·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·U KhanY Yiannakou
Apr 22, 2006·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Donald M BushnellChristopher R McBurney
Jul 5, 2016·Frontiers in Oncology·Karin S CoyneSam H Ahmedzai
Dec 19, 2017·PloS One·Jilles M FermontUNKNOWN By-Band-Sleeve Study Management Group
Jul 2, 2014·The American Journal of Gastroenterology·Sveta ShahDaniel A Leffler
Feb 19, 2010·Journal of Glaucoma·Ke-Hung ChienJiann-Torng Chen
Feb 24, 2017·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Francesca FerrettiLuca Elli
Apr 17, 2020·Nature Reviews. Gastroenterology & Hepatology·Christopher J Black, Alexander C Ford
Nov 28, 2020·Journal of Crohn's & Colitis·Sara TadbiriUNKNOWN GETAID-IBD-disk study group
Sep 2, 2021·United European Gastroenterology Journal·Zsa Zsa R M WeertsDaniel Keszthelyi
Mar 30, 2021·Journal of Clinical Gastroenterology·Sabrina BerensJonas Tesarz
Sep 22, 2021·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Rosel SturkenboomBrigitte A B Essers

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

International Journal of Cancer. Journal International Du Cancer
Robert A SikesLeland W K Chung
Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
Jeffrey M LacknerLeonard A Katz
Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
Jeffrey M LacknerKenneth Holroyd
Scandinavian Journal of Gastroenterology
S J Lewis, K W Heaton
© 2022 Meta ULC. All rights reserved