Performing an early systematic Doppler-ultrasound fails to prevent hemorrhagic complications after complex partial nephrectomy

Therapeutic Advances in Urology
Inès DominiqueMarc Olivier Timsit

Abstract

The aim of this work was to assess the clinical relevance of a systematic postoperative Doppler-ultrasound (DU) after complex partial nephrectomy (PN). All patients who underwent open, laparoscopic or robotic PN from 2014 to 2017 at our institution were included. Postoperative hemorrhagic complications (HCs) were defined as the occurrence of blood transfusion, hemorrhagic shock, arterial embolization, or re-hospitalization for hematoma. DU was systematically performed between post-op day 4 and 7 for every complex tumor (RENAL score ⩾ 7). DU was considered positive in the presence of pseudoaneurysm (PA) or arteriovenous fistula (AVF). Among 194 patients, 117 underwent DU (60.3%). We reported 22 HCs (11.3%) requiring 8 selective embolization procedures (4.1%). HCs occurred during the hospital stay in 17 patients (77.3%), thus directly diagnosed on a computed tomography scan. Among the five patients (22.7%) with HC occurring after hospital discharge, between day 7 to 15, four had a previously negative systematic DU. Overall, systematic DU was positive in only five patients (4.3%) with only one patient of 194 (0.5%) undergoing preventive embolization of a PA-AVF. The negative predictive values (NPVs) and positive predictive values ...Continue Reading

References

Dec 14, 2004·The Journal of Urology·Anup P RamaniInderbir S Gill
Nov 11, 2005·The Journal of Urology·Dinesh Singh, Inderbir S Gill
Jun 19, 2007·The Journal of Urology·Inderbir S GillAndrew C Novick
Dec 17, 2009·Archives of Internal Medicine·Rebecca Smith-BindmanDiana L Miglioretti
Jun 22, 2010·World Journal of Urology·C NetschA J Gross
Sep 21, 2010·Radiology·Stephanie R Wilson, Peter N Burns
Mar 13, 2012·European Urology·Steven MacLennanUNKNOWN EAU Renal Cancer Guideline Panel

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