Performing slow vital capacity in older people with and without cognitive impairment--is it useful?

Age and Ageing
S C AllenP Yeung

Abstract

most patients with moderate cognitive impairment are unable to perform forced spirometry. It has been suggested that slow vital capacity (SVC) is easier to perform than forced vital capacity (FVC) because it requires less understanding and co-ordination. We conducted a study to determine whether that assertion is correct. we studied 83 inpatients, mean age 83 years (range 67-95, 51 female). They had measurements made of FVC, SVC and the Mini-Mental State Examination (MMSE). The spirometry was conducted using the European Respiratory Society/American Thoracic Society standards. of the 83 subjects, 38 were able to do both FVC and SVC and 32 were unable to do either. The overall concordance was 84%. Twelve were able to do SVC but not FVC (eight due to excessive cough, two due to weakness and two had an MMSE < 24 with poor co-ordination). An inability to do neither FVC nor SVC was predicted by an MMSE < 24/30 (P < 0.0001) with a sensitivity of 88% and specificity of 67%. SVC is not a usable substitute for FVC for elderly patients with cognitive impairment but is of some utility for those who tend to cough. An MMSE < 24/30 is predictive of inability to perform FVC and SVC.

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Nov 1, 1995·American Journal of Respiratory and Critical Care Medicine·N Carvalhaes-NetoI Macquin-Mavier
Jul 21, 1998·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·S K Chhabra
Apr 14, 2000·American Journal of Respiratory and Critical Care Medicine·V BelliaF Rengo
Sep 3, 2002·Journal of the Royal Society of Medicine·T J Hendra
Jan 24, 2003·Age and Ageing·Licia PezzoliCarlo Vergani
Dec 25, 2003·Thorax·A MoodyD Forman
Feb 5, 2004·Thorax·J K Stoller
Aug 2, 2005·The European Respiratory Journal·M R MillerUNKNOWN ATS/ERS Task Force
Jan 24, 2007·Respiratory Medicine·Astri Medbø, Hasse Melbye
Dec 7, 2007·Respiratory Research·Lennart NathellKjell Larsson
Jul 1, 2006·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Stuart L Silverman

❮ Previous
Next ❯

Citations

Jul 17, 2012·The Medical Clinics of North America·Kristina L Bailey
Jul 24, 2015·NPJ Primary Care Respiratory Medicine·Eralda TurkeshiJean-Marie Degryse
Mar 9, 2017·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·R RufinoR M Dias
Mar 24, 2018·Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration·Noah LechtzinJinsy A Andrews
Jan 1, 2014·Clinical Investigation·Sabrina PaganoniJames D Berry

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.