Perfusion and diffusion MR imaging in enhancing malignant cerebral tumors

European Journal of Radiology
Cem CalliTaner Akalin

Abstract

Common contrast-enhancing malignant tumors of the brain are glioblastoma multiforme (GBMs), anaplastic astrocytomas (AAs), metastases, and lymphomas, all of which have sometimes similar conventional MRI findings. Our aim was to evaluate the role of perfusion MR imaging (PWI) and diffusion-weighted imaging (DWI) in the differentiation of these contrast-enhancing malignant cerebral tumors. Forty-eight patients with contrast-enhancing and histologically proven brain tumors, 14 AAs, 17 GBMs, nine metastases, and eight lymphomas, were included in the study. All patients have undergone routine MR examination where DWI and PWI were performed in the same session. DWI was performed with b values of 0, 500, and 1000 mm(2)/s. Minimum ADC values (ADC(min)) of each tumor was later calculated from ADC map images. PWI was applied using dynamic susceptibility contrast technique and maximum relative cerebral blood volume (rCBV(max)) was calculated from each tumor, given in ratio with contralateral normal white matter. Comparisons of ADC(min) and rCBV(max) values with the histological types of the enhancing tumors were made with a one-way analysis of variance and Bonferroni test. A P value less than 0.05 indicated a statistically significant dif...Continue Reading

References

Feb 1, 1990·Radiology·B L DeanR G Carey
Jul 1, 1997·Neuroradiology·K KrabbeF Madsen
Feb 25, 1999·Journal of Magnetic Resonance Imaging : JMRI·T SugaharaM Takahashi
Jun 3, 1999·Radiology·E A KnoppI I Kricheff
Apr 5, 2000·AJR. American Journal of Roentgenology·J C WongJ R Petrella
Apr 5, 2001·European Journal of Radiology·R LuypaertM Osteaux
Sep 25, 2002·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Sung Ki ChoJong Hyun Kim
Dec 4, 2003·European Journal of Radiology·Christoph PreulJohann Link

❮ Previous
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Citations

Nov 28, 2012·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Massoud AkhtariMark Mandelkern
Jan 12, 2011·Clinical Nuclear Medicine·Nalan CanMustafa Unlü
Nov 5, 2008·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Alan JacksonSamantha Mills
Sep 1, 2012·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·S J MillsA Jackson
May 28, 2010·Neurologia Medico-chirurgica·Hirofumi OyamaKuniaki Tanahashi
May 22, 2008·AJR. American Journal of Roentgenology·Nobuyuki KosakaHarumi Itoh
Aug 27, 2013·AJR. American Journal of Roentgenology·Marco EssigMeng Law
Dec 29, 2010·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Naomi MoritaHiromu Nishitani
Nov 1, 2012·CNS Oncology·Joachim M Baehring, Robert K Fulbright
Jul 11, 2013·Computational and Mathematical Methods in Medicine·Toshihiko YamasakiRyuji Murakami
Mar 19, 2014·Skeletal Radiology·Alexey Surov, Curd Behrmann
Feb 22, 2012·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Cameron M McDougallRobert W Broad
Sep 13, 2013·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Luana StanescuMarguerite T Parisi
Dec 3, 2014·Neurologic Clinics·Thomas J PfiffnerLaszlo Mechtler
May 25, 2012·The British Journal of Radiology·G ThompsonA Jackson
Jul 10, 2010·AJNR. American Journal of Neuroradiology·I S HaldorsenE-M Larsson
Oct 31, 2012·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Ioannis TsougosEftychia Kapsalaki
May 4, 2011·Clinical Neuroradiology·J FaehndrichE Hattingen
Sep 26, 2015·AJNR. American Journal of Neuroradiology·K YamashitaH Honda
Nov 26, 2011·Journal of Neuroradiology. Journal De Neuroradiologie·Antoine GodefroyEmmanuel Gerardin
Aug 28, 2010·Magnetic Resonance Imaging·Xiang LiuSven Ekholm
Aug 17, 2010·Neuroimaging Clinics of North America·Gerard ThompsonAlan Jackson

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