Perfusion CT is superior to angiography in predicting pancreatic necrosis in patients with severe acute pancreatitis.

Journal of Gastroenterology
Yoshihisa TsujiTsutomu Chiba

Abstract

We performed perfusion computed tomography (P-CT) and angiography of the pancreas in patients with severe acute pancreatitis (SAP) and compared the usefulness of these two methods in predicting the development of pancreatic necrosis. We compared P-CT and angiography results taken within 3 days after symptom onset in 21 SAP patients. We divided the pancreas into three areas, the head, body, and tail, and examined each area for perfusion defects (via P-CT) and arterial vasospasms (by angiography). Three weeks later, all patients underwent contrast-enhanced CT to determine whether pancreatic necrosis had developed. Of the 21 SAP patients, 16 exhibited perfusion defects, while 17 proved positive for vasospasms in at least one area. Fourteen patients developed pancreatic necrosis. Of the 63 pancreatic areas from the 21 SAP patients, perfusion defects appeared in 25 areas (39.7%), 24 of which showed vasospasms (96.0%). Angiography showed 33 areas with vasospasms (52.4%), of which 24 showed perfusion defects (72.7%). Of the 25 areas with perfusion defects, 21 developed pancreatic necrosis (84.0%). Of the 33 areas with vasospasms, 21 developed necrosis (63.6%). Pancreatic necrosis developed only in the areas positive both for perfusion...Continue Reading

References

Nov 1, 1994·Radiology·E J BalthazarE vanSonnenberg
Nov 24, 1999·International Journal of Pancreatology : Official Journal of the International Association of Pancreatology·H G Beger, R Isenmann
Jul 18, 2002·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·K TakedaS Matsuno
Jul 18, 2002·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·R IsenmannH G Beger
Dec 14, 2002·Radiologic Clinics of North America·Emil J Balthazar
Nov 27, 2004·Radiology·Leon Axel
Mar 8, 2005·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·L William Traverso, Richard A Kozarek
Apr 16, 2005·Gut·UNKNOWN Working Party of the British Society of GastroenterologyUNKNOWN Association of Upper GI Surgeons of Great Britain and Ireland
Dec 17, 2005·AJR. American Journal of Roentgenology·Pierre E BizePierre-Alexandre Poletti
Apr 12, 2006·The British Journal of Surgery·C M Cuthbertson, C Christophi
Jun 15, 2006·The American Journal of Gastroenterology·Gianpiero ManesGeneroso Uomo
Aug 17, 2006·Journal of Gastroenterology and Hepatology·Yoshihisa TsujiHiroshi Yamamoto
Nov 24, 2006·Annals of Surgery·Gunilla E EckerwallRoland G Andersson
Oct 24, 2007·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Yoshihisa TsujiTsutomu Chiba
Nov 7, 2007·The British Journal of Surgery·T L BollenUNKNOWN Dutch Acute Pancreatitis Study Group
Jan 7, 2009·The British Journal of Surgery·M G BesselinkUNKNOWN Dutch Acute Pancreatitis Study Group
Apr 27, 2010·Pancreas·Yoshihisa TsujiRyuichirou Doi

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Citations

Apr 21, 2012·International Journal of Inflammation·Yoshihisa TsujiChiba Tsutomu
Aug 19, 2011·Indian Journal of Endocrinology and Metabolism·Vikas Chaudhary, Shahina Bano
Nov 22, 2013·Abdominal Imaging·Hai-ou LiBin Zhao
Feb 14, 2016·Cancer Medicine·Milica StefanovićMatthias Löhr
Aug 30, 2016·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Ajay Kumar YadavAshish Datt Upadhyay
Apr 22, 2017·The Cochrane Database of Systematic Reviews·Oluyemi KomolafeKurinchi Selvan Gurusamy
Jul 13, 2020·Journal of Hepato-biliary-pancreatic Sciences·Akira YamamiyaAtsushi Irisawa
Nov 26, 2015·World Journal of Gastroenterology : WJG·Samira M SadowskiLeo Bühler

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