Perfusion magnetic resonance imaging: comparison of semiologic characteristics in first-pass perfusion of brain tumors at 1.5 and 3 Tesla

Journal of Neuroradiology. Journal De Neuroradiologie
Natacha MauzS Grand

Abstract

To investigate whether using 3 Tesla (T) instead of 1.5T modifies the data obtained from first-pass perfusion in relation to the quantitative values of cerebral blood volume (CBV) and estimation of micro-vascular leakage (MVL). To describe the differences in data in the setting of neuro-oncology cases and propose explanations based on the discrepancies. In total, 21 patients presenting an intracranial intra-axial space-occupying lesion underwent two MRI explorations, one at 1.5T and another at 3T, including a first-pass perfusion sequence using sequence parameters, defined by the manufacturer Philips. Using a gamma variate analysis, the ratio of cerebral blood volume (rCBV) in tumor, peritumoral, and normal appearing areas was first assessed. After a global analysis, a subgroup analysis was conducted according to the rCBV value measured at 1.5T. Lastly, MVL was assessed based on the signal intensity recorded above baseline after the passage of the contrast medium. At 3T, compared to 1.5T data that are currently the reference, rCBV was constantly and significantly over-evaluated (P=0.0041 for all tumors), while MVL was constantly and significantly under-evaluated (P<0.0001 for all tumors). The increase in magnetic field strength...Continue Reading

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Citations

Jun 21, 2014·Journal of Neurosurgery. Pediatrics·Duc Ha HoangAlexandre Krainik
Feb 26, 2013·Journal of Neuroradiology. Journal De Neuroradiologie·Serhat TokgozMuzaffer Mutluer
Jul 9, 2014·Diagnostic and Interventional Imaging·A RaimbaultJ-P Cottier
Sep 10, 2014·Diagnostic and Interventional Imaging·R GuillevinC Guillevin
Dec 21, 2014·Neuro-oncology·Lambros TselikasCatherine Oppenheim
Jul 24, 2013·Diagnostic and Interventional Imaging·S GrandA Krainik
Jun 25, 2020·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Gurvan DissauxUlrike Schick

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