PMID: 698870Sep 1, 1978Paper

Perfusion of malignant hyperthermia susceptible and normal isolated pig livers with halothane

Canadian Anaesthetists' Society Journal
B A BrittG M Kent

Abstract

We have perfused malignant hyperthermia susceptible and normal isolated pig livers with halothane for one hour. The liver temperatures, oxygen and carbon dioxide tensions, the base deficits and lactate concentrations in blood entering and leaving the liver have been measured at the beginning and at the end of the perfusion. Statistical analysis has shown that there are no significant differences in these parameters between the beginning and the end of the perfusion period or between the normal and the malignant hyperthermia susceptible livers. We conclude, therefore, that the livers of malignant hyperthermia susceptible pigs are either normal or else, if abnormal, the abnormalities are sufficiently benign as to be not measurably expressed.

References

Nov 1, 1978·Circulation·V F HuckellJ E Morch
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Dec 1, 1976·Journal of the Science of Food and Agriculture·K S Cheah, A M Cheah
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Oct 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·N Friedmann, C R Park
Jan 1, 1974·The Journal of Membrane Biology·A B Borle
Jul 1, 1973·Canadian Anaesthetists' Society Journal·B A BrittN B Rewcastle
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Sep 1, 1966·Canadian Anaesthetists' Society Journal·W G Cullen
Mar 1, 1965·Scientific American·K R PORTER, C FRANZINI-ARMSTRONG

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Citations

Dec 1, 1981·Acta Anaesthesiologica Scandinavica·J A Aldrete

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