PMID: 15376767Sep 21, 2004Paper

Perfusion technique for nonhaemic cardiopulmonary bypass prime in neonates and infants under 6 kg body weight

Perfusion
Frank MerkleRoland Hetzer

Abstract

Cardiopulmonary bypass (CPB) in neonates and infants is associated with significant haemodilution when priming of the CPB circuit is accomplished without transfusion of homologous blood components. The degree of haemodilution and, thus, the requirements for blood transfusion may be reduced when the CPB circuit is miniaturized without compromising patient safety. Between January 2002 and October 2003, selected neonates and small infants were operated on using a nonhaemic prime extracorporeal circuit. CPB priming volume could be reduced from 300 mL to 190 mL by using a dedicated neonatal CPB console with mast-mounted roller pump heads. Reduction of priming volume resulted from shortening of all CPB lines to the minimum, downsizing of all CPB lines, exclusion of unused CPB components, use of vacuum-assisted venous drainage and from close co-operation between the perfusionist, cardiac surgeon and anaesthesiologist. The reduction in priming volume was achieved without eliminating the arterial line filter as safety device. A total of nine patients weighing between 3.2 and 5.9 kg (mean 4.7 kg) and with a body surface area of 0.22-0.35 m2 (mean 0.29 m2) were operated on with the use of the modified neonatal CPB circuit and a nonhaemic ...Continue Reading

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Citations

Dec 12, 2013·Biomedizinische Technik. Biomedical Engineering·Georg WagnerJutta Arens
Jul 23, 2008·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Shigang WangAkif Undar
Nov 29, 2007·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Yasuhiro KotaniShunji Sano
Oct 11, 2017·Anesthesia and Analgesia·Jill M CholetteNabil Hassan
Nov 1, 2011·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Mirela BojanPascal Vouhé
Nov 29, 2007·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Yves Durandy
May 31, 2014·Seminars in Cardiothoracic and Vascular Anesthesia·Craig M McRobbMark D Twite
Nov 29, 2007·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Shinya UgakiShunji Sano
Jan 12, 2013·Artificial Organs·Fabrizio De RitaGiovanni Battista Luciani
Dec 3, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Jingchun WuHarvey S Borovetz

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