PMID: 38354Sep 1, 1979

Perfusion techniques of the canine pancreas for physiological and secretin response studies

The Japanese Journal of Surgery
S Teranishi, K Okajima


In vivo and in situ perfusion techniques of the canine pancreas for physiologic and secretin response to studies are described. We developed these modified techniques to clarify the mechanism of the pancreatic exocrine secretion. An analysis was made of some physiological parameters of the pancreas and our findings were compared with those obtained in secretin stimulation of the pancreas. The composition of secretin induced venous effluent and pancreatic juice was investigated. A decrease of pH, pO2 and (HCO-3) in the venous blood and a temporary efflux of K+ from the cell to the perfusate were observed after secretin stimulation. A temporary decrease of perfusion pressure was observed after secretin stimulation and the change is thought to be due to vascular dilatation. Ultrastructural findings from the pancreas perfused for about 1 hour showed no prominent changes.


May 24, 2003·Memórias do Instituto Oswaldo Cruz·Joselita Maria Mendes dos SantosGloria Alícia Diaz Rodriguez


Jan 1, 1974·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·M R EloyJ F Grenier
Jan 1, 1973·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·W MeyerR C Lillehei
Aug 1, 1970·The Journal of Surgical Research·M M Rao, R G Elmslie
Aug 1, 1970·The International Journal of Applied Radiation and Isotopes·S B Lupica
Jan 1, 1971·The American Journal of Digestive Diseases·H D RitchieA D Maclean
May 1, 1968·The Journal of Physiology·R M CaseT Scratcherd
Nov 1, 1963·Annals of Surgery·G L NARDID B SKINNER
Apr 23, 1926·The Journal of Physiology·B P Babkin, E H Starling

Related Concepts

Venous Blood Substance
Pancreatic Exocrine Secretion
Portion of Venous Blood
Benign Tumor of Pancreas
Secretin Measurement
Body Surface Area Formula for Dogs
Pancreatic Juice

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