Perfusion weighted color maps for enhanced visualization of myocardial infarction by MSCT: preliminary experience.

The International Journal of Cardiovascular Imaging
Andreas H MahnkenMichael Scheuering

Abstract

The reliable detection of myocardial perfusion defects and myocardial infarction (MI) is of great interest in the comprehensive workup of coronary artery disease. The aim of this study was to optimize the ability of contrast-enhanced cardiac multislice spiral computed tomography (MSCT) for detecting hypoperfused myocardium as surrogate marker of MI using a newly developed post-processing technique. First a model-based software tool for semi-automated detection of the long axis of the left ventricle and assignment of left-ventricular segments was developed using a region growing algorithm and a point distribution model. To visualize changes of the myocardial contrast enhancement pattern color coding was performed after spreading of the attenuation values. 15 patients (12 men, mean age 57 +/- 15 years) with a history of MI underwent cardiac MSCT (16 x 0.75 mm, 120 kV, 550 mA s(eff.), 100 ml Iopromide) and contrast enhanced delayed enhanced magnetic resonance imaging (DE-MRI) after administration of 0.2 mmol Gd-DTPA/kg/bodyweight as reference standard. Presence of infarction was assessed from MSCT, post-processed MSCT images and DE-MRI using a 17-segment model of the left ventricle. On DE-MRI MI was present in 78/255 myocardial se...Continue Reading

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Citations

Aug 20, 2014·The British Journal of Radiology·A M BucherB Ruzsics
Aug 30, 2008·The International Journal of Cardiovascular Imaging·James StirrupS Richard Underwood
Jun 29, 2010·Journal of Cardiovascular Computed Tomography·Andreas H Mahnken
Feb 26, 2015·AJR. American Journal of Roentgenology·Akos Varga-SzemesU Joseph Schoepf
Apr 2, 2011·Expert Review of Cardiovascular Therapy·Andreas H Mahnken
Feb 24, 2012·AJR. American Journal of Roentgenology·Rozemarijn VliegenthartU Joseph Schoepf
Dec 25, 2008·Expert Review of Cardiovascular Therapy·Jacob M van WerkhovenJeroen J Bax
Nov 14, 2017·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Kevin KaliszPrabhakar Rajiah
Jul 3, 2018·Current Cardiovascular Imaging Reports·Bryan C RamseyDustin M Thomas

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