Periampullary and pancreatic incidentaloma: a single institution's experience with an increasingly common diagnosis.

Annals of Surgery
Jordan M WinterCharles J Yeo

Abstract

While incidental masses in certain organs have received particular attention, periampullary and pancreatic incidentalomas (PIs) remain poorly characterized. We reviewed 1944 consecutive pancreaticoduodenectomies (PD) over an 8-year period (April 1997 to October 2005). A total of 118 patients (6% of all PDs) presented with an incidental finding of a periampullary or pancreatic mass. The PI patients were analyzed and compared with the rest of the cohort (NI, nonincidentaloma group, n = 1826). Thirty-one percent of the PI patients (n = 37) had malignant disease (versus 76% of the NI patients, P < 0.001), 47% (n = 55) had premalignant disease, and the remaining 22% (n = 26) had little or no risk for malignant progression. The 3 most common diagnoses in the PI group were IPMN without invasive cancer (30%), cystadenoma (17%), and pancreatic ductal adenocarcinoma (10%). The PI group had a higher overall complication rate (55% versus 43%, P = 0.02), due in part to a significantly increased rate of pancreatic fistulas (18.4% PI versus 8.5% NI, P < 0.001). Patients in the PI group with malignant disease had a superior long-term survival (median, 30 months, P = 0.01) compared with patients in the NI group with malignant disease (median, 2...Continue Reading

References

Aug 7, 1999·Annals of Oncology : Official Journal of the European Society for Medical Oncology·F Treitschke, H G Beger
Mar 25, 2000·Endocrinology and Metabolism Clinics of North America·R Udelsman, E K Fishman
Mar 25, 2000·Endocrinology and Metabolism Clinics of North America·D C Aron, T A Howlett
Sep 9, 2000·Harefuah·A Ishay, U Ben Shlomo
May 3, 2002·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Steven A AhrendtHenry A Pitt
Jul 20, 2002·AJR. American Journal of Roentgenology·Michael Brant-Zawadzki
Nov 15, 2002·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Michael N Brant-Zawadzki
Dec 20, 2002·Current Opinion in Oncology·Geoffrey B Thompson, William F Young
Jan 31, 2003·Annales de cardiologie et d'angéiologie·O VancollieJ Donckier
Apr 11, 2003·Archives of Surgery·Carlos Fernández-del CastilloAndrew L Warshaw
Jul 24, 2003·AJR. American Journal of Roentgenology·Otha W LintonUNKNOWN National Council on Radiation Protection and Measurements
May 18, 2004·The Surgical Clinics of North America·Robert J Silver, Sareh Parangi
May 29, 2004·Annals of Surgery·Taylor A SohnKeith D Lillemoe
Jul 27, 2004·Radiology·David J Brenner, Carl D Elliston
Sep 24, 2004·Current Biology : CB·Mariko KondoManfred Schartl
Nov 9, 2004·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Chi Leung LiuJohn Wong
Dec 24, 2004·AJR. American Journal of Roentgenology·Stephen J HandrichMichael G Sarr
Jan 27, 2005·Radiology·Molly T BeinfeldG Scott Gazelle
Mar 18, 2005·Seminars in Ultrasound, CT, and MR·Jamie Mitchell, Sareh Parangi
Jun 4, 2005·ANZ Journal of Surgery·Erica L Whineray KellyRichard Harman
Sep 28, 2006·Hormones : International Journal of Endocrinology and Metabolism·Dimitrios A Linos

❮ Previous
Next ❯

Citations

Mar 12, 2011·Abdominal Imaging·Margaret GoodmanR Brooke Jeffrey
Feb 20, 2008·Langenbeck's Archives of Surgery·Jan-Bart M KoorstraAnirban Maitra
May 24, 2007·Journal of Hepato-biliary-pancreatic Surgery·Ralph H HrubanMichael Goggins
Apr 19, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Charles GalanisCharles J Yeo
Jun 26, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Matthias H SeeligWaldemar Uhl
Dec 25, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Marshall S BakerHenry A Pitt
Nov 28, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·C J LeeD M Simeone
Jan 9, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Teviah SachsCharles M Vollmer
Jan 20, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Naveen B KrishnaBanke Agarwal
Mar 28, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·John W KunstmanRonald R Salem
Apr 5, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Zhi Ven FongJordan M Winter
Aug 2, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Jordan M CloydJeffrey A Norton
Sep 30, 2008·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Seung-Mo HongMichael Goggins
Mar 9, 2011·Nature Reviews. Gastroenterology & Hepatology·Hanno MatthaeiAnirban Maitra
Jan 27, 2010·Gastroenterology·Anirban Maitra
Dec 17, 2011·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Seung-Mo HongMichael Goggins
Jun 4, 2008·Annals of Surgical Oncology·Lee M OcuinDavid A Kooby
Oct 26, 2012·AJR. American Journal of Roentgenology·Elizabeth H DibbleRathan M Subramaniam
Oct 17, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Hop S Tran CaoMatthew H G Katz
Nov 26, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Cynthia E WeberGerard V Aranha
Nov 19, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Niloufar DuschMarco Niedergethmann
Jun 7, 2014·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Michael ClerveusCarlos Moreno-Sanz
Oct 9, 2014·Advances in Surgery·Katherine E PorukSean J Mulvihill
Aug 6, 2014·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Grace C LeeCarlos Fernández-del Castillo
Dec 17, 2014·Case Reports in Oncological Medicine·Mazen E IskandarAvram M Cooperman
Jul 20, 2011·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Gavin LowEdward Leen
Mar 8, 2014·World Journal of Gastroenterology : WJG·Ming-Chu ChangYu-Ting Chang
Jan 12, 2010·Surgical Endoscopy·Pier Cristoforo GiulianottiAndrea Coratti
Mar 30, 2007·Digestive Diseases and Sciences·Madhusudhan R SanakaJuan Palazzo
Jul 14, 2007·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·U Hopt, T Keck
Mar 26, 2010·Langenbeck's Archives of Surgery·Thilo WelschJan Schmidt
Sep 4, 2013·Langenbeck's Archives of Surgery·Reto M KäppeliIgnazio Tarantino
Feb 7, 2012·Best Practice & Research. Clinical Endocrinology & Metabolism·Xeily ZárateMiguel F Herrera
Dec 17, 2014·World Journal of Surgical Oncology·Amit SastryAvram M Cooperman
May 12, 2015·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Miguel F HerreraGregory Randolph
May 14, 2016·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Renato CostiClaudio Bassi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved