Perifollicular xanthomatosis as the hallmark of axillary Fox-Fordyce disease: an evaluation of histopathologic features of 7 cases

Archives of Dermatology
Adolfo B BormateTimothy H McCalmont

Abstract

Fox-Fordyce disease (FFD) or apocrine miliaria is a rare condition with features that are characteristic clinically but not histopathologically. It is traditionally described as a condition that shows infundibular plugging, acanthosis, parakeratosis, spongiosis, and a nonspecific infiltrate. The so-called retention vesicle, which reputedly involves the apocrine duct, is often difficult to find. Recently, 4 uncontrolled observations were described (infundibular dyskeratotic cells, vacuolar alteration, cornoid lamella-like parakeratosis, and perifollicular foamy macrophages). In this study, we evaluated both established and new histopathologic criteria for the diagnosis of FFD and searched for other meaningful findings. Most established features were observed in both patients with FFD and control patients. All cases occurred during 1995 through 2005. No unequivocal retention vesicle was identifiable in any case. Infundibular vacuolar change and cornoid lamella-like parakeratosis were not corroborated as being diagnostically meaningful. Few dyskeratotic cells were seen in some patients with FFD and in control patients. Perifollicular foam cells were noted in most patients with FFD but not among control patients. These cells expres...Continue Reading

Citations

Nov 29, 2012·Indian Journal of Sexually Transmitted Diseases and AIDS·Rashmi MahajanFreny Bilimoria
Dec 19, 2013·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Monique M ElseviersLuc Van Bortel
Apr 3, 2012·Pharmacogenomics·Jesse J Swen, Henk Jan Guchelaar
Oct 24, 2013·European Journal of Clinical Pharmacology·Emmanuel EschmannJürg Blaser
Dec 12, 2012·Pharmacogenomics·Rianne M F van SchieAnke-Hilse Maitland-van der Zee
Oct 24, 2012·European Journal of Clinical Pharmacology·H Abdullah-KoolmeesE R Heerdink
Sep 6, 2011·Journal of the American Medical Informatics Association : JAMIA·Willemijn L EppengaPeter A G M De Smet
Jan 16, 2013·Lasers in Medical Science·Josiane HelouGrace Obeid
Jan 1, 2012·Scientifica·Paul A F Jansen, Jacobus R B J Brouwers
Nov 2, 2011·BMC Family Practice·Dorien L M ZwartCordula Wagner
May 23, 2009·The American Journal of Dermatopathology·Ricardo S Macarenco, Juan Carlos Garces S
Sep 19, 2009·Pharmacogenomics·Rianne M F van SchieAnke Hilse Maitland-van der Zee
Nov 20, 2012·Journal of Nutrition in Gerontology and Geriatrics·Roschelle Heuberger
Jan 23, 2010·BMC Health Services Research·Sander GaalMichel Wensing
Mar 23, 2011·British Journal of Haematology·Martina TeichertLoes E Visser
Oct 11, 2011·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Aileen B DequitoJos G W Kosterink
Nov 19, 2011·Journal of the American Geriatrics Society·A Clara Drenth-van MaanenRob J van Marum
Jan 11, 2012·The Consultant Pharmacist : the Journal of the American Society of Consultant Pharmacists·Maha SaadLori Katinas
Dec 3, 2011·Wiener klinische Wochenschrift·Eva MannBernhard Iglseder
Jun 9, 2012·Pharmacoepidemiology and Drug Safety·Antonio Pintor-MármolMaria José Faus
Nov 28, 2012·Journal of Cutaneous Pathology·Gene H KimPaola Rodriguez
Oct 16, 2012·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Priya Bahri, Mira Harrison-Woolrych
Sep 18, 2013·British Journal of Clinical Pharmacology·Thomas BürkleRenke Maas
Jan 30, 2015·Current Medical Research and Opinion·Hannah K DoodyRonald L Castelino
Feb 17, 2015·Pharmacoepidemiology and Drug Safety·Margaretha F Warlé-van HerwaardenPeter A G M De Smet
Apr 7, 2017·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Nibu Parameswaran NairLuke R Bereznicki
May 10, 2017·Journal of Medical Systems·Fatih BaypinarMatthijs L Becker
Apr 30, 2017·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·McVin Hua Heng CheenGiat Yeng Khee
Aug 5, 2017·European Journal of Clinical Pharmacology·Caterina Bigi, Guido Bocci
Jun 3, 2018·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Kei OuchiEdward W Boyer
Jul 12, 2018·Expert Opinion on Drug Safety·Tesfahun C EshetieLisa M Kalisch Ellett
Dec 12, 2018·Health Communication·Victor J B HuiskesBart J F van den Bemt
Mar 19, 2019·Expert Opinion on Drug Metabolism & Toxicology·L E J PeetersJ Versmissen
Jun 11, 2019·Acta Clinica Belgica·Julie HiasLorenz Van der Linden
Aug 29, 2009·The Journal of Dermatology·Pei-Han KaoJulia Yu-Yun Lee
Mar 23, 2011·European Journal of Clinical Pharmacology·Esther V UijtendaalToine C G Egberts
Aug 31, 2012·Pharmacoepidemiology and Drug Safety·Linda HärmarkKees van Grootheest
Oct 17, 2012·International Journal of Dermatology·Cristina N Brau JavierJorge L Sanchez

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.

Related Papers

The Journal of Dermatology
Pei-Han KaoJulia Yu-Yun Lee
Journal of the American Academy of Dermatology
M E StashowerG W Turiansky
Pediatric Dermatology
Kamaldeep SandhuA J Kanwar
Journal of the American Academy of Dermatology
A S ColtonA P Kowalczyk
Journal of the American Academy of Dermatology
M J GlennA P Kelly
© 2022 Meta ULC. All rights reserved