PMID: 18407167Oct 1, 1993Paper

Perifused pituitary cells as a model for studies of gonadotropin biosynthesis and secretion

Trends in Endocrinology and Metabolism : TEM
J Weiss, J Larry Jameson

Abstract

Pituitary gonadotropes are influenced by a variety of hormones in vivo. In an effort to study these signals individually, several experimental models have been devised. One of these models, pituitary perifusion, has the dual advantage of removing endogenous hormones and growth factors and permitting exogenous signals to be applied in a continuous or pulsatile fashion. Application of the perifusion model to the study of gonadotropen biosynthesis and secretion has led to the discovery of several previously unappreciated interactions between hypothalamic and paracrine signals that act on gonadotropes.

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Citations

Nov 13, 1998·Cell Biology International·O A BrownR G Goya
May 24, 2000·Life Sciences·O A BrownR G Goya
Nov 18, 1998·Mechanisms of Ageing and Development·O A BrownR G Goya
May 16, 2000·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·O A BrownR G Goya
Apr 11, 2009·Archives of Gynecology and Obstetrics·Shabeen Naz Masood, Muhammad Faraz Masood
Feb 7, 1998·The Journal of Biological Chemistry·L B DraperT K Woodruff
Dec 9, 1998·The American Journal of Physiology·K HeinzeA R Midgley

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