PMID: 6981402Sep 1, 1982Paper

Perilymphatic and endolymphatic PO2. Variations during anoxia, hyperoxia, and hypercapnia

Archives of Otolaryngology
J Prazma

Abstract

Cochlear microcirculation was studied with oxygen-sensitive microelectrodes simultaneously in all three scalas during anoxia, hyperoxia, and hypercapnia. The anoxia caused a sharp decline of Po2 in the scala media (SM), scala vestibuli (SV), and scala tympani (ST). Hyperoxia and hypercapnia resulted in an elevation of Po2 in all three scalas. During anoxia, the SM showed the earliest and largest decline in Po2, with the shortest recovery and reoxygenation time. When Po2 slopes (during anoxia) were compared, the SM to ST and the SM to SV were substantially different and remained different even when the partial pressures of oxygen quantified as oxygen in nanomoles. Our experiments also showed that changes in Po2 within the SM closely correlate with changes of endocochlear potential and BP.

Citations

Jan 1, 1991·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·M KawakamiH Takahashi
Nov 1, 1989·Hearing Research·J PrazmaH C Pillsbury
Jan 1, 1987·Hearing Research·L D FechterA L Nuttall
Jan 1, 1991·Acta Oto-laryngologica·K YamamotoT Matsunaga
Nov 1, 1988·American Journal of Otolaryngology·J M Miller, H Dengerink
Oct 29, 2000·The Annals of Otology, Rhinology, and Laryngology·H Yamamoto, K Makimoto
Aug 1, 1991·Circulation Research·K A OhlsénJ M Miller
Jan 1, 1997·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·F ScheibeH Baumgärtl
Feb 4, 2003·Journal of Applied Physiology·David J Doolette, Simon J Mitchell
Dec 16, 2006·The Journal of Physiological Sciences : JPS·Yoshitsugu NimuraTakahiro Kubota
Nov 1, 1988·American Journal of Otolaryngology·A L Nuttall

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