Perinatal asphyxia, hypoxia, ischemia and hearing loss. An overview
Birth hypoxia, asphyxia and ischemia have often been thought to be major causes of early hearing loss or deafness. The purpose of the present review is to focus on the role of these particular factors for perinatal auditory disorders. On the whole, only a small proportion of neonatal hearing loss is caused by perinatal factors. The exact etiology of neonatal hearing loss in children with complicated deliveries is difficult to evaluate due to the large number of causative factors that might be involved. After reviewing the literature covering the past 15-20 years, it is not possible to say that we understand the relative importance of different factors and their interactions. However, in the majority of studies, birth asphyxia is not correlated with hearing loss in babies with complicated deliveries Prolonged artificial ventilation, the presence of severe hypoxic ischemic encephalopathy or persistent pulmonary hypertension are important factors. The brain is more susceptible to anoxia than the ear and both are more likely to be damaged after prolonged pre-, peri- and postnatal hypoxia-ischemia than pure hypoxia during delivery. Perinatal hypoxia is more likely to cause a temporary hearing loss than a permanent one. Preterm babie...Continue Reading
Anoxic-ischemic encephalopathy in the human neonatal period. The significance of brain stem involvement
Profile and stability of sensorineural hearing loss in persistent pulmonary hypertension of the newborn
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Developmental temporal bone anatomy and its clinical significance: variations on themes by H. F. Schuknecht
Hearing loss in very preterm and very low birthweight infants at the age of 5 years in a nationwide cohort
Long-term effect of perinatal and postnatal asphyxia on developing human auditory brainstem responses: peripheral hearing loss
Functional impairment of the auditory pathway after perinatal asphyxia and the short-term effect of perinatal propofol anesthesia in lambs
Effects of hypoxic-ischemic encephalopathy and whole-body hypothermia on neonatal auditory function: a pilot study.
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Resveratrol attenuates CoCl2-induced cochlear hair cell damage through upregulation of Sirtuin1 and NF-κB deacetylation
Follow-up of 5- to 11-year-old children treated for persistent pulmonary hypertension of the newborn
Brain-stem auditory impairment during the neonatal period in term infants after asphyxia: dynamic changes in brain-stem auditory evoked response to clicks of different rates
Hearing and neurological impairment in children with history of exchange transfusion for neonatal hyperbilirubinemia
Speech and language development in a population of Swedish hearing-impaired pre-school children, a cross-sectional study
Differential changes in peripheral and central components of the brain stem auditory evoked potentials during the neonatal period in term infants after perinatal hypoxia-ischemia
Two-year survival and mental and psychomotor outcomes after the Norwood procedure: an analysis of the modified Blalock-Taussig shunt and right ventricle-to-pulmonary artery shunt surgical eras
Analysis of auditory function using brainstem auditory evoked potentials and auditory steady state responses in infants with perinatal brain injury
Relationship between brainstem auditory function during the neonatal period and depressed Apgar score
Perinatal Asphyxia and Brain Development: Mitochondrial Damage Without Anatomical or Cellular Losses
Cost-effectiveness of inhaled nitric oxide in near-term and term infants with respiratory failure: eighteen- to 24-month follow-up for Canadian patients
Postnatal functional status of the brainstem auditory pathway in term infants after perinatal hypoxia-ischemia.
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