PMID: 9440251Jan 24, 1998Paper

Perinatal estrogen exposure: later repercussion on the fertility of rats

Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology
O C M PereiraC P Carlos

Abstract

The aim of the present study was to investigate the effects of perinatal estrogen exposure in the fertility of rats. Thus, rats were treated with estrogen on the 21st or 22nd day of intra-uterine life or treated with estrogen immediately after birth. It was observed that the testicular descent of males and beginning of puberty of females were advanced in all estrogen-treated groups. The females from estrogen-treated groups showed reduced frequency of estrous in 15 consecutive days of study, and there was an increase in estrous duration. Their fertility also were impaired and a reduction in the number of alive fetuses, as well as enhancement of pre- and postimplantation loss, mainly in the group treated with estrogen on the 21st day of intra-uterine life. However, the alterations observed in the fertility of estrogen-treated male rats were slighter and only females mated with male rats from the group treated with estrogen immediately after birth showed enhanced preimplantation loss. We suggest that the reproductive function is impaired by exposure to estrogen in the perinatal life of rats, and that the mechanisms involved in this effect are distinct for males and females.

References

Sep 1, 1985·Biology of Reproduction·C BellidoE Aguilar
Mar 20, 1981·Science·N J MacLusky, F Naftolin
Jan 1, 1984·Annual Review of Neuroscience·A P Arnold, R A Gorski
Oct 1, 1981·The Journal of Endocrinology·F GoganC Kordon
Jan 1, 1980·Endocrinology·N R KallaD L Loriaux
Feb 16, 1995·Brain Research. Developmental Brain Research·L L DonCarlosD M Stancik
Jan 1, 1996·Physiology & Behavior·C P CarlosO C Marques Pereira

❮ Previous
Next ❯

Citations

Jan 29, 2002·Pharmacology, Biochemistry, and Behavior·Daniela C C Gerardin, Oduvaldo C M Pereira
Feb 26, 2003·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·O C M PereiraD C C Gerardin
Nov 30, 2002·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·A C Arena, O C M Pereira
Jun 10, 2014·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Chen ChenYongzhong Qian
Sep 20, 2005·Pharmacology, Biochemistry, and Behavior·Camilla Moreira Ribeiro, Oduvaldo Câmara Marques Pereira
Nov 24, 2004·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·R C Piffer, O C M Pereira

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
O C M PereiraD C C Gerardin
Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas
S A AlmeidaT L Lamano Carvalho
© 2021 Meta ULC. All rights reserved