PMID: 18719292Aug 23, 2008Paper

Perinatal exposure to brominated flame retardants and polychlorinated biphenyls in Japan

Endocrine Journal
Yukiko KawashiroChisato Mori

Abstract

Brominated flame retardants (BFRs) are used to prevent combustion in consumer products. Examples of BFRs are polybrominated diphenyl ethers (PBDEs), tetrabromobisphenol A (TBBPA), and tribromophenol (TBP). These compounds are reported to have adverse effects on human health and endocrine disrupting effects. The purpose of this study was to identify the Japanese perinatal exposure to PBDEs, hydroxylated PBDE metabolites (OH-PBDEs), TBBPA, and TBP compared with polychlorinated biphenyls (PCBs) and hydroxylated PCB metabolites (OH-PCBs). We investigated the concentrations of these compounds in maternal blood, maternal milk, cord blood, and umbilical cords from 16 Japanese mother-infant pairs by HRGC/HRMS. PBDEs were detected in all samples of maternal blood (mean+/-SD; median=25+/-23 pg/g; 18 pg/g wet weight), maternal milk (140+/-220 pg/g; 59 pg/g wet weight), cord blood (4.8+/-6.5 pg/g; 1.6 pg/g wet weight), and umbilical cords (3.1+/-3.1 pg/g; 2.1 pg/g wet weight). The mothers were divided into two groups, a high-concentration group and a low-concentration group. The percentage of BDE-47 showed the greatest difference between the two groups. 6-OH-BDE-47, TBBPA, and TBP were detected in all umbilical cord samples (mean+/-SD; med...Continue Reading

References

Jun 1, 1997·Journal of Human Lactation : Official Journal of International Lactation Consultant Association·R L BreitzkaF K Hatzopoulos
Apr 2, 1998·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·U Orn, E Klasson-Wehler
May 16, 2000·Environmental Health Perspectives·K Hooper, T A McDonald
Jun 28, 2000·Toxicological Sciences : an Official Journal of the Society of Toxicology·I A MeertsA Brouwer
Mar 27, 2001·Environmental Health Perspectives·G Charnley, R M Putzrath
Aug 29, 2001·Journal of Environmental Monitoring : JEM·C ThomsenG Becher
Nov 14, 2001·Archives of Environmental Contamination and Toxicology·L HovanderE Klasson Wehler
Feb 12, 2002·Environmental Health Perspectives·Frederica P PereraVirginia A Rauh
May 10, 2002·Environmental Science & Technology·Cathrine ThomsenGeorg Becher
May 10, 2002·Chemosphere·Thomas A McDonald
Jun 18, 2002·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·H HakkE Klasson-Wehler
Aug 2, 2002·Toxicological Sciences : an Official Journal of the Society of Toxicology·Ilonka A T M MeertsAbraham Brouwer
Sep 3, 2002·Environmental Health Perspectives·Britta FängströmAke Bergman
Jun 20, 2003·Drug Metabolism and Disposition : the Biological Fate of Chemicals·Anna MorckEva Klasson Wehler
Jul 5, 2003·Environmental Health Perspectives·Anita MazdaiRobert M Bigsby
Jul 10, 2003·Environment International·Isao Watanabe, Shin-ichi Sakai
Jul 10, 2003·Environment International·Heldur Hakk, Robert J Letcher
Nov 5, 2003·Environmental Health Perspectives·Arnold SchecterRobin Rosen
Nov 6, 2003·Toxicology in Vitro : an International Journal Published in Association with BIBRA·J C RíosM Repetto
Dec 31, 2003·Environmental Health Perspectives·Linda S Birnbaum, Daniele F Staskal
Apr 20, 2004·Toxicology Letters·Naemi FukudaMakoto Ema
Sep 2, 2005·International Journal of Environmental Health Research·Manuel GutiérrezRicardo Barra
Jan 13, 2006·Toxicological Sciences : an Official Journal of the Society of Toxicology·Daniele F StaskalLinda S Birnbaum
Mar 2, 2006·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·J M SandersL T Burka
May 24, 2006·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Y TadaH Kamimura
Apr 3, 2007·Environmental Science & Technology·Nerissa WuThomas F Webster
Jul 13, 2007·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Maja MyrenLisbeth Ehlert Knudsen
Aug 23, 2007·Environmental Science & Technology·Daniel CarrizoMaties Torrent
Oct 17, 2007·Environmental Health Perspectives·Katharina Maria MainJorma Toppari
Feb 6, 2008·Toxicology Letters·Yuhe HePaul K S Lam
Oct 28, 2009·Human & Experimental Toxicology·Yukiko KawashiroChisato Mori

❮ Previous
Next ❯

Citations

Jun 24, 2011·Environmental Science and Pollution Research International·Belén GómaraAke Bergman
Oct 12, 2012·Environmental Health and Preventive Medicine·Aya HisadaJun Yoshinaga
Jul 17, 2013·Chemosphere·Agnieszka HernikJan Krzysztof Ludwicki
Jul 28, 2011·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Stéphanie Decherf, Barbara A Demeneix
Jan 16, 2010·Journal of Toxicology and Environmental Health. Part a·Tae Hyung KimHyung Sik Kim
Jun 29, 2012·Toxicological Sciences : an Official Journal of the Society of Toxicology·Claudio A ErraticoStelvio M Bandiera
Jul 6, 2010·Environmental Health : a Global Access Science Source·Marie FrederiksenLisbeth E Knudsen
Dec 27, 2013·Asian Journal of Andrology·Moosa FanibandBo A G Jönsson
Feb 4, 2014·Environment International·Esther VizcainoAdonina Tardon
Mar 19, 2014·The Science of the Total Environment·Gyuyeon ChoiJeongim Park
Sep 23, 2014·Ecotoxicology and Environmental Safety·M EzechiášT Cajthaml
Dec 25, 2015·Environment International·Christopher LeonettiHeather M Stapleton
Dec 15, 2012·Pharmacological Reports : PR·Elżbieta ZiemińskaJerzy W Lazarewicz
Apr 13, 2012·International Journal of Hygiene and Environmental Health·Tye E ArbuckleDouglas L Arnold
Jan 13, 2012·Chemosphere·M EzechiášT Cajthaml
Oct 7, 2011·International Journal of Hygiene and Environmental Health·Michael HoopmannRoland Suchenwirth
May 18, 2010·International Journal of Hygiene and Environmental Health·Marie FrederiksenLisbeth E Knudsen
Sep 29, 2015·International Journal of Hygiene and Environmental Health·H FrommeW Völkel
Aug 9, 2015·Molecular and Cellular Biochemistry·Ewelina Honkisz, Anna K Wójtowicz
Sep 24, 2015·Environmental Science and Pollution Research International·Akifumi EguchiChisato Mori
May 10, 2015·Toxicology Letters·Claudio ErraticoAdrian Covaci
Dec 25, 2010·Neurotoxicology·Lucio G Costa, Gennaro Giordano
Jan 17, 2012·Environmental Pollution·Yukiko FujiiKoichi Haraguchi
Apr 29, 2015·Environmental Science and Pollution Research International·Johan FångÅke Bergman
Feb 16, 2015·Environmental Research·Sihem Ben HassineMohamed Ridha Driss

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.