Perinatal management of SARS-CoV-2 infection in a level III University Hospital.

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Susana PissarraHenrique Soares

Abstract

Over the past 4 months, SARS-CoV-2 pandemic has spread all over the world. The lack of understanding of this pandemic epidemiological characteristics, clinical implications and long term consequences have raised concern among healthcare workers. Pregnant women and newborns are a particularly worrisome population since data referring to real infection impact in these patients are scarce and management controversial. We report on the perinatal management of the first consecutive ten mother-infant dyads of SARS-CoV-2 infection complicated pregnancy. All mothers were included in newborn management planning prior to delivery and decided on separation from their newborns; nine decided on postponing breastfeeding until SARS-CoV-2 negativity while maintaining lactation stimulation. No evidence of vertical transmission was found (all NP swab and bronchial secretions SARS-CoV-2 RT-PCR were negative). No newborn developed clinical evidence of infection. In the face of current scientific uncertainty, decisions of perinatal management, such as mother-infant separation and breastfeeding, must involve parents in a process of shared decision making.

References

Mar 3, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Xiaotong WangXinghua Shen
Mar 7, 2020·Emerging Infectious Diseases·Yang LiJifang Sheng
Mar 13, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Shaoshuai WangLing Feng
Apr 1, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Federica CapannaGian Carlo Di Renzo
Apr 8, 2020·Acta Obstetricia Et Gynecologica Scandinavica·Mehreen Zaigham, Ola Andersson
Apr 9, 2020·Frontiers in Pediatrics·Yan ChenYalan Liu
Apr 18, 2020·The New England Journal of Medicine·Lian ChenJie Qiao
Apr 18, 2020·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Pu YangDongchi Zhao
Apr 20, 2020·Journal of Infection and Public Health·Zhoujie PengYuan Shi
Apr 21, 2020·Breastfeeding Medicine : the Official Journal of the Academy of Breastfeeding Medicine·Guglielmo SalvatoriAndrea Campana
May 2, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Ziyi YangYi Liu
Mar 27, 2020·MedRxiv : the Preprint Server for Health Sciences·R. NieLei Jin

❮ Previous
Next ❯

Citations

Jun 3, 2021·Journal of Clinical Medicine·Katarzyna Grudlewska-BudaKrzysztof Skowron

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.