PMID: 59015Jun 26, 1976

Perinatal mortality and birth-weight in relation to aspirin taken during pregnancy

S ShapiroD Slone


In a cohort of 41 337 gravidas and their offspring in the U.S.A. there was no evidence that aspirin taken in pregnancy is a cause of stillbirth, neonatal death, or reduced birth-weight. The women were divided into those who were not exposed to aspirin (14 956), those with intermediate exposure (24 866), and those who were heavily exposed (1515). Stillbirth-rates were similar for all three groups. Differences in neonatal death-rates and mean birth-weights were slight and none were statistically significant. Trends were opposite among approximately equal numbers of White and Black children.


Jan 1, 1983·Pharmacology & Therapeutics·J V Aranda, L Stern
Mar 1, 1996·Toxicology Letters·D P DavisA L Kraus
May 1, 1994·Reproductive Toxicology·E Robert, A R Scialli
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Apr 1, 1983·The Journal of Clinical Investigation·T F Ferris, E K Weir
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Dec 18, 2007·Obstetrical & Gynecological Survey·Andra H JamesThomas Price
May 23, 2014·The Journal of Toxicological Sciences·Akihito YamashitaHitoshi Funabashi

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