Perinatal outcomes of spontaneous twins compared with twins conceived through intracytoplasmic sperm injection

Journal of Perinatal Medicine
Burcu Saygan-KaramürselLütfü Onderoğlu

Abstract

To compare perinatal outcomes in spontaneous twins compared with those conceived by intracytoplasmic sperm injection (ICSI). Retrospective case-control study. Cases consisted of 274 intracytoplasmic sperm injection twins, controls were 348 naturally conceived twins delivered between 1999 and 2003 in a tertiary hospital. Birth weight, gestational age at birth, cesarean delivery rate, perinatal mortality and morbidity, congenital anomalies, gestational diabetes and pregnancy induced hypertension. Preterm deliveries (76.6% vs. 64.1% <37 weeks and 19.7% vs. 13.2% <32 weeks) and low birth weight (73% vs. 60.3% <2500 g and 19.7% vs. 12.6% <1500 g) were significantly higher in the ICSI group compared with controls. Gestational diabetes mellitus (8% vs. 2.9%) and cesarean deliveries (95.2% vs. 77.6%) were more common in cases compared with the control group. There was a significantly higher rate of perinatal morbidity (16.4% vs. 7.8%) and mortality (8% vs. 2.6%) in ICSI twins. The incidence of congenital malformations diagnosed at birth was higher in cases (4.4%) compared with controls (0.9%) but the difference was not significant when adjusted for maternal age. Perinatal outcomes of twins after ICSI treatment are less optimal than nat...Continue Reading

References

Jan 1, 1997·Acta Obstetricia Et Gynecologica Scandinavica·T AgustssonG Mires
Mar 1, 1997·Obstetrics and Gynecology·J BernaskoR L Berkowitz
Feb 3, 1998·Journal of Assisted Reproduction and Genetics·M DhontP De Sutter
Aug 4, 1998·Human Reproduction·J MoiseR Gale
Nov 20, 1998·American Journal of Obstetrics and Gynecology·B P FitzsimmonsM R Fluker
Mar 12, 1999·BMJ : British Medical Journal·A G SutcliffeB A Lieberman
Nov 26, 1999·Human Reproduction·M BonduelleA Van Steirteghem
Mar 31, 2000·Human Reproduction·U B WennerholmB Källén
Mar 8, 2002·The New England Journal of Medicine·Michèle HansenSandra Webb
May 23, 2002·American Journal of Human Genetics·Gerald F CoxBernhard Horsthemke
Nov 7, 2002·Reproductive Biomedicine Online·Michael Ludwig, Alexander Katalinic
Nov 20, 2002·American Journal of Human Genetics·Michael R DeBaunAndrew P Feinberg
Feb 1, 2003·Lancet·Annette C MollFlora E van Leeuwen
Oct 2, 2003·American Journal of Obstetrics and Gynecology·Anwar H NassarAntoine A Abu-Musa

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Citations

Apr 13, 2012·Journal of Human Hypertension·C ThomopoulosC Stefanadis
Mar 2, 2013·Human Reproduction Update·Michèle HansenCarol Bower
Mar 2, 2011·Pediatrics·Rajan WadhawanUNKNOWN Eunice Kennedy Shriver National Institute of Child Health & Human Development Neonatal Research Network
Mar 19, 2014·European Journal of Obstetrics, Gynecology, and Reproductive Biology·M AshrafiM Chehrazi
Mar 9, 2010·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Shi Wu WenMark C Walker
Sep 8, 2018·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Jing ZhaoYanping Li
Oct 2, 2019·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Saman MaroufizadehReza Omani-Samani
Jul 27, 2007·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·N N Sarkar

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