PMID: 11920726Mar 29, 2002Paper

Perineal muscles and motoneurons are sexually monomorphic in the naked mole-rat (Heterocephalus glaber)

Journal of Neurobiology
Maria E PeroulakisNancy G Forger

Abstract

Naked mole-rats are eusocial mammals that live in colonies with a single breeding female and one to three breeding males. All other members of the colony, known as subordinates, are nonreproductive and exhibit few sex differences in behavior or genital anatomy. This raises questions about the degree of sexual differentiation in subordinate naked mole-rats. The striated perineal muscles associated with the phallus [the bulbocavernosus (BC), ischiocavernosus (IC), and levator ani (LA) muscles], and their innervating motoneurons, are sexually dimorphic in all rodents examined to date. We therefore asked whether perineal muscles and motoneurons were also sexually dimorphic in subordinate naked mole-rats. Muscles similar to the LA and IC of other rodents were found in naked mole-rats of both sexes. No clear BC muscle was identified, although a large striated muscle associated with the urethra in male and female naked mole-rats may be homologous to the BC of other rodents. There were no sex differences in the volumes of the LA, IC, or the urethral muscles. Motoneurons innervating the perineal muscles were identified by retrograde labeling with cholera-toxin-conjugated horseradish peroxidase. All perineal motoneurons were found in a s...Continue Reading

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Citations

Apr 25, 2003·Brain Research. Developmental Brain Research·S Hadi MansouriCatherine Ulibarri
Jun 28, 2011·Brain, Behavior and Evolution·Jeff J AnyanMelissa M Holmes
Oct 16, 2009·PloS One·Marianne L SeneyNancy G Forger
Jun 9, 2007·Proceedings of the National Academy of Sciences of the United States of America·Melissa M HolmesNancy G Forger
May 7, 2009·Frontiers in Neuroendocrinology·Melissa M HolmesNancy G Forger
Jun 28, 2008·Neuroscience·G J RosenN G Forger
Jan 1, 2010·Molecular Ecology Resources·K KatsushimaY Matsuda
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Dec 22, 2006·The Journal of Comparative Neurology·Greta J RosenNancy G Forger
Feb 17, 2017·Physiological Reviews·Vladimir P SkulachevViktor A Sadovnichii
Feb 7, 2020·Physiology·Rochelle BuffensteinHolly M Brown-Borg

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