Perineural spread of pelvic malignancies to the lumbosacral plexus and beyond: clinical and imaging patterns

Neurosurgical Focus
Stepan CapekRobert J Spinner

Abstract

OBJECT Perineural spread along pelvic autonomie nerves has emerged as a logical, anatomical explanation for selected cases of neoplastic lumbosacral plexopathy (LSP) in patients with prostate, bladder, rectal, and cervical cancer. The authors wondered whether common radiological and clinical patterns shared by various types of pelvic cancer exist. METHODS The authors retrospectively reviewed their institutional series of 17 cases concluded as perineural tumor spread. All available history, physical examination, electrodiagnostic studies, biopsy data and imaging studies, evidence of other metastatic disease, and follow-up were recorded in detail. The series was divided into 2 groups: cases with neoplastic lumbosacral plexopathy confirmed by biopsy (Group A) and cases included based on imaging characteristics despite the lack of biopsy or negative biopsy results (Group B). RESULTS Group A comprised 10 patients (mean age 69 years); 9 patients were symptomatic and 1 was asymptomatic. The L5-S1 spinal nerves and sciatic nerve were most frequently involved. Three patients had intradural extension. Seven patients were alive at last follow-up. Group B consisted of 7 patients (mean age 64 years); 4 patients were symptomatic, 2 were asym...Continue Reading

References

Mar 1, 1975·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·R E Johnson, T C Pomeroy
Jan 1, 1985·Neurology·K A JaeckleK M Foley
Sep 1, 1985·The Annals of Otology, Rhinology, and Laryngology·J G Batsakis
Feb 1, 1980·Medical Hypotheses·S Seely
Jan 1, 1994·Diseases of the Colon and Rectum·T J SaclaridesS G Economou
Jul 1, 1997·Journal of Surgical Oncology·T TakahashiH Katoh
Jul 1, 1999·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·G MoalemM Schwartz
Jul 21, 1999·Journal of Neurosurgery·M MaxwellN T Zervas
Feb 18, 2003·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·B Baader, M Herrmann
Mar 19, 2003·Spine·Toru TakadaMasahiro Kurosaka
Sep 3, 2004·Cancer Research·Gustavo E AyalaDavid Rowley
Oct 26, 2005·The Prostate·Gustavo E AyalaThomas M Wheeler
May 19, 2006·Cancer Research·Gustavo E AyalaTimothy C Thompson
Sep 27, 2007·Pancreas·Masato KayaharaTetsuo Ohta
Nov 6, 2007·The Spine Journal : Official Journal of the North American Spine Society·Kenzo UchidaHisatoshi Baba
Oct 3, 2008·Medical Oncology·George OrphanosGeorge Kitrou
Jun 2, 2009·Cancer·Catherine LiebigDaniel Albo
Aug 13, 2009·Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada·Shilo LefresneDon Yee
Mar 6, 2010·The Lancet Oncology·Lukas RobHelena Robova
May 1, 2010·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Jung Wook HuhYoung Jin Kim
May 18, 2010·Acta neurochirurgica·Marie-Noëlle Hébert-BlouinRobert J Spinner
Oct 13, 2010·Nature Reviews. Urology·Fausto PetrelliSandro Barni
Sep 24, 2011·Nature Reviews. Cancer·Aditi A BapatHaiyong Han

❮ Previous
Next ❯

Citations

Jul 18, 2016·Journal of the Neurological Sciences·W GrisoldW N Löscher
Apr 23, 2016·Muscle & Nerve·Zsuzsanna ArányiZsuzsanna Göcsei
Jan 29, 2019·Clinical Nuclear Medicine·Patrícia Barros GouveiaLuís Hugo da Silva Trindade Duarte
Dec 22, 2017·Acta neurochirurgica·Joshua J JacobsKristin R Swanson
Aug 12, 2020·European Journal of Nuclear Medicine and Molecular Imaging·Koichiro KimuraUkihide Tateishi
Jul 10, 2019·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Stephanie NougaretYulia Lakhman
Jul 24, 2020·Skeletal Radiology·Rodrigo LunaShivani Ahlawat
Apr 9, 2020·Journal of Gynecologic Oncology·Noriaki SakuragiHidemichi Watari
Sep 21, 2018·Wiener medizinische Wochenschrift·Wolfgang GrisoldAnna Grisold
Apr 17, 2021·Clinics in Geriatric Medicine·Jonathan SarezkyKara Stavros
Jul 27, 2021·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Robert J Spinner

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Related Concepts

Related Feeds

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.