Perineurium originates from fibroblasts: demonstration in vitro with a retroviral marker

Science
M B BungeJ R Sanes

Abstract

A cellular sheath, the perineurium, forms a protective barrier around fascicles of nerve fibers throughout the peripheral nervous system. In a study to determine the cellular origin of perineurium, a culture system was used in which perineurium forms after purified populations of sensory neurons, Schwann cells, and fibroblasts are recombined. Before recombination, the Schwann cells or the fibroblasts were labeled by infection with a defective recombinant retrovirus whose gene product, beta-galactosidase, is histochemically detectable in the progeny of infected cells. Perineurial cells were labeled when fibroblasts had been infected but not when Schwann cells had been infected. Thus, perineurium arises from fibroblasts in vitro and, by implication, in vivo as well.

Citations

Sep 5, 2002·Journal of Neuroscience Research·Cynthia L JordanRobert J Handa
Aug 1, 1995·Journal of Neuroscience Research·B T ZhangT Takenaka
Jun 1, 1994·Muscle & Nerve·C CrisciG Caruso
Jan 1, 1991·Acta Neuropathologica·H Grehl, J M Schröder
Jan 1, 1991·Acta Neuropathologica·J M VallatM Dumas
Jan 1, 1994·Acta Neuropathologica·J L BradleyP J Watkins
Jul 1, 1991·Journal of Neurocytology·F ScaravilliE Sinclair
Jan 1, 1989·Trends in Neurosciences·J R Sanes
Jun 1, 1994·Progress in Neurobiology·K C Wadhwani, S I Rapoport
Jan 1, 1993·Clinical Neurology and Neurosurgery·J M SchröderJ Weis
Apr 27, 2000·Atherosclerosis·M R DashwoodJ Y Jeremy
Feb 28, 2003·Journal of Neuroscience Methods·Jan ManentMarco Giovannini
Aug 11, 1999·Trends in Neurosciences·K R Jessen, R Mirsky
Jan 5, 2002·Journal of Physiology, Paris·Rhona MirskyDurward Lawson
Jan 8, 2008·Nature Neuroscience·Sarah KucenasBruce Appel
Oct 13, 2012·Nature Protocols·Rossukon KaewkhawJohn W Haycock
Jul 2, 2002·Journal of Anatomy·K R Jessen, R Mirsky
May 23, 2009·The American Journal of Dermatopathology·Stewart F Cramer
Dec 27, 2011·The American Journal of Dermatopathology·Stewart F Cramer, Andrey Fesyuk
Aug 30, 2008·The American Journal of Surgical Pathology·Alireza ZarinehMichael S Rabkin
Dec 8, 2007·Anatomical Science International·Hiroyuki Kudoh, Tatsuo Sakai
Oct 1, 1991·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·N G BeamishA Oldfors
Jan 1, 1990·Annals of the New York Academy of Sciences·M B BungeR P Bunge
Dec 10, 1999·Annals of the New York Academy of Sciences·R MirskyK R Jessen
Jan 4, 2013·Stem Cells Translational Medicine·Elizabeth A SalisburyElizabeth A Olmsted-Davis
Oct 9, 2002·Journal of the Peripheral Nervous System : JPNS·Perttu M TerhoMatias Röyttä
Apr 25, 2008·Advances in Anatomic Pathology·Sergio Piña-Oviedo, Carlos Ortiz-Hidalgo
May 1, 1993·The Journal of Comparative Neurology·A A ZalewskiR N Azzam

❮ Previous
Next ❯

Related Concepts

Related Feeds

CZI Human Cell Atlas Seed Network

The aim of the Human Cell Atlas (HCA) is to build reference maps of all human cells in order to enhance our understanding of health and disease. The Seed Networks for the HCA project aims to bring together collaborators with different areas of expertise in order to facilitate the development of the HCA. Find the latest research from members of the HCA Seed Networks here.

BRAIN Initiative Cell Census Network (BICCN)

The BRAIN Initiative Cell Census Network aims to identify and provide experimental access to the different brain cell types to determine their roles in health and disease. Discover the latest research from researchers in the BRAIN Initiative Cell Census Network here.