Periocular necrotising fasciitis: a multicentre case series

The British Journal of Ophthalmology
Saul N RajakDinesh Selva

Abstract

Necrotising fasciitis (NF) is a severe infection of deep subcutaneous soft tissues with high morbidity and mortality. Periocular necrotising fasciitis (PONF) is a very rare condition with many unanswered questions about the presentation and management. We present a retrospective case series of patients with PONF from three centres in Australia and two in the UK to investigate the clinical and microbiological characteristics and outcomes and report on patients treated with antibiotics alone. Twenty-nine patients (20 men; 69%) with PONF were identified and followed up for between 2 months and 10 years (median 57, mean 52.6 months) between 1990 and 2013. Conditions associated with chronic immunocompromise were present in 16/29 (55%). Twenty-one (75%) recalled minor periocular trauma or an infected lesion, two having been assaulted by the same assailant. Systemic shock occurred in 6/29 (21%) patients and 1 died. Group A, β-haemolytic Streptococcus was the most common bacterium identified (25/29, 86%). Intravenous antibiotics were used in all patients, and up to five tissue debridements were required to control the disease in 23/29 (74%); reconstructive surgery was required in 12/29 (41%) patients. One patient died from the disease ...Continue Reading

References

Jan 1, 1991·Eye·G E RoseM R Watts
Jun 1, 1988·The British Journal of Ophthalmology·R Walters
Jun 15, 1985·British Medical Journal·C J Brun-BuissonJ Revuz
May 1, 1995·Annals of Surgery·C R McHenryM A Malangoni
Dec 1, 1995·American Journal of Ophthalmology·A ShayeganiM E Grossman
Dec 31, 1997·Ophthalmology·D H MarshallJ A Nerad
Feb 19, 1998·American Journal of Ophthalmology·D R JordanD H Marshall
Oct 8, 1999·American Journal of Ophthalmology·I J SuñerD T Tse
Sep 26, 2006·Ophthalmology·Victor M ElnerAdam S Hassan
Nov 10, 2009·The British Journal of Ophthalmology·Davide LazzeriMarcello Pantaloni
Jun 19, 2010·Internal Medicine·Taro Shimizu, Yasuharu Tokuda
Apr 24, 2012·Acta Ophthalmologica·Shantha AmrithWong Wan Ling
May 15, 2013·Orbit·Rhujuta MehtaAlan McNab
Dec 18, 2013·The British Journal of Surgery·T GohC H Wong
Jun 21, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Dennis L StevensJames C Wade
Aug 20, 2014·The British Journal of Ophthalmology·P W FlavahanS R Drummond

❮ Previous
Next ❯

Citations

Mar 17, 2017·Survey of Ophthalmology·Alan D Proia
Feb 24, 2018·BMJ Case Reports·Zahra N Jaffer, Cherie Nicholson
Mar 11, 2018·BMJ Case Reports·Laura LeachNazir Bhat
Jul 31, 2019·Acta Ophthalmologica·Natacha Storm WürtzSteffen Heegaard
Sep 22, 2020·European Journal of Plastic Surgery·Shameem A HaqueAlexander Woollard
May 17, 2018·Journal of Surgical Case Reports·Paola Eiben, Sancho Rodriguez-Villar
Dec 30, 2020·BMJ Case Reports·Grace Anne McCabeThomas Gordon Campbell
Nov 9, 2020·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Cassie A CameronDinesh Selva
Jun 22, 2018·Case Reports in Ophthalmology·Tri Rejeki HerdianaHirohiko Kakizaki

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Cellulitis

Cellulitis (erysipelas) is a recurring and debilitating bacterial infection of the skin and underlying tissue. Discover the latest research on cellulitis here.

Related Papers

Wounds : a Compendium of Clinical Research and Practice
Pascal SteenvoordeGerrolt Jukema
Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
Sonali Prabhakar KhadakkarAshish Gupta
The Laryngoscope
M L ShindoW R Dougherty
© 2021 Meta ULC. All rights reserved