PMID: 8471814Apr 1, 1993Paper

Periodic respiration in patients with heart failure

The Clinical Investigator
S AndreasH Kreuzer

Abstract

Patients with heart failure are known to demonstrate periodic respiration (PR) during sleep. The factors causing PR are not well known. We therefore studied 20 patients (aged 18-66 years) with idiopathic dilated cardiomyopathy. Full-night polysomnography and evaluation of respiration and transcutaneous oxygen saturation were performed. Hypercapnic ventilatory response (HCVR) was evaluated during daytime. The patients showed PR for 25 +/- 26% (mean +/- standard deviation) of total sleep time. During PR, oxygen desaturated 7.1 +/- 4.6%. Sleep was impaired. HCVR was normal. Oxygen desaturation during PR was predicted by HCVR (r = 0.47, P < 0.05) and left atrial diameter (r = 0.60, P < 0.05). The time period of PR expressed as a fraction of total sleep time was correlated with HCVR (r = 0.45, P < 0.05) and left atrial diameter (r = 0.51, P < 0.05). In conclusion, PR with oxygen desaturation, arousals, and impaired sleep was observed in stable heart failure. HCVR and left heart dimensions were related to PR. These findings confirm the concept of a feedback loop describing respiratory control in PR.

Citations

Jan 1, 1996·European Journal of Applied Physiology and Occupational Physiology·K MeyerH Roskamm
Jan 1, 1996·Respiration Physiology·M C KhooC S Houston
Dec 1, 1996·The American Journal of Cardiology·S AndreasH Kreuzer
Feb 24, 2001·The Annals of Thoracic Surgery·M S SlaughterP S Pappas
Aug 18, 2004·Sleep Medicine Reviews·M T Naughton
Aug 18, 2004·Sleep Medicine Reviews·M T Naughton
Jun 18, 2003·Respiratory Physiology & Neurobiology·Kingman P Strohl
Feb 5, 2000·The New England Journal of Medicine·I WilcoxC E Sullivan
Jun 20, 2006·Respiratory Physiology & Neurobiology·Zbigniew L ToporJohn E Remmers
Apr 29, 1998·Clinics in Chest Medicine·M T Naughton, T D Bradley
Feb 14, 2002·Journal of Applied Physiology·Fang HanKingman P Strohl
Aug 12, 2003·Journal of Applied Physiology·Edwin R PriceKingman P Strohl

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.