Periodontal disease and risk for neuropathic foot ulceration in type 2 diabetes

Diabetes Research and Clinical Practice
Luciana AbraoHelena Schmid

Abstract

Diabetic neuropathy (DN) has been associated with oral dryness, tooth loss and an increased risk for foot ulceration, but the association between periodontal problems and DN has not been fully elucidated. This study investigated whether the risk for neuropathic foot ulceration (DM-NFUR) was associated with periodontal disease (PD) in patients with type 2 diabetes mellitus. This cross-sectional study examined 122 patients with type 2 diabetes for PD; findings were compared with results for presence of DM-NFUR. PD severity was classified as none/mild (NM-PD), moderate/severe (MS-PD) and edentulous (E). NM-PD was found in 40.2% patients; MS-PD, in 32.0%; and 27.8% were edentulous. DM-NFUR was detected in 18.4% of the patients in the NM-PD group, in 68.2% in the MS-PD group, and in 61.8% of completely edentulous individuals. PD was significantly correlated with DM-NFUR (p<or=0.001). After adjustment for sex, age, diabetes duration, dental health care and education, PD and edentulism were independently associated with DM-NFUR (odds ratio(adjusted); 6.6; 95% CI 2.3-18.8; p<or=0.001, and odds ratio(adjusted) 4.9; 95% CI 1.6-15.3; p<or=0.01). Patients with DM-NFUR have substantially more MS-PD and edentulism. Further studies should eva...Continue Reading

References

Jan 1, 1991·The Journal of Diabetic Complications·P G NewrickR J Corrall
Aug 1, 1990·Diabetes Care·R G NelsonW C Knowler
Dec 1, 1993·The Journal of the American Dental Association·R C Oliver, T Tervonen
Apr 1, 1993·Diabetes Care·G Cherry-Peppers, J A Ship
Aug 1, 1997·Journal of Periodontology·S G GrossiR J Genco
Feb 24, 1998·Archives of Internal Medicine·D G ArmstrongJ G Fleischli
Sep 2, 1998·Annals of Periodontology·S G Grossi, R J Genco
Sep 13, 2000·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·H L CollinJ H Meurman
Jun 26, 2001·Journal of Clinical Periodontology·J Katz
Oct 13, 2001·Journal of Dental Research·T SaitoA Ohshima
Apr 30, 2002·Diabetes Care·Zachary T Bloomgarden
Jan 30, 2004·Diabetes Care·Hidetaka NomaHiromu K Mishima
Dec 24, 2004·Diabetes Care·Aramesh SaremiWilliam C Knowler
Mar 16, 2005·Journal of Clinical Periodontology·Mine KiranMurat Faik Erdoğan
Jun 28, 2005·Dental Clinics of North America·Jasim M Albandar
Nov 9, 2005·Journal of Periodontology·Khalaf F Al-ShammariHom-Lay Wang
Nov 10, 2005·Journal of Periodontology·James D Beck, Steven Offenbacher
Apr 25, 2007·Journal of Dental Research·N PischonT Pischon

❮ Previous
Next ❯

Citations

Sep 17, 2015·Current Diabetes Reports·Wenche S BorgnakkeAnca Jivanescu
Jun 1, 2012·Worldviews on Evidence-based Nursing·Wendy A GiffordNancy Lefebre
Jul 14, 2021·Journal of Periodontal Research·Xuexue ZhangQiuyan Li

❮ Previous
Next ❯

Related Concepts

Related Feeds

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.

Biomarkers for Type 2 Diabetes

Biomarkers can help understand chronic diseases and assist in risk prediction for prevention and early detection of diseases. Here is the latest research on biomarkers in type 2 diabetes, a disease in which the body is unable to produce or properly use insulin.

Related Papers

American Journal of Critical Care : an Official Publication, American Association of Critical-Care Nurses
D CorteseS McKinley
Journal of the Medical Association of Thailand = Chotmaihet Thangphaet
Siribang-On Piboonniyom KhovidhunkitWeerapan Khovidhunkit
Indian Journal of Dermatology, Venereology and Leprology
Nirmala MarkendeyaC R Srinivas
Journal of Diabetes and Its Complications
Gun E Sandberg, Karin F Wikblad
© 2021 Meta ULC. All rights reserved