Periodontal findings in Cohen syndrome with chronic neutropenia

Journal of Periodontology
S AlaluusuaS Pirinen

Abstract

Radiographic periodontal status and microbiological findings of periodontal pockets in subjects with Cohen syndrome are presented in this report. This hereditary disorder causes mental retardation, and neutropenia is one feature of the syndrome. Fifteen patients with Cohen syndrome and 15 controls matched for age and sex and, as far as possible, according to the degree of mental retardation were examined. Alveolar bone loss was evaluated from the panoramic radiographs. Two subgingival samples were obtained from the most affected anterior and posterior periodontal sites in each dentate subject and examined for the occurrence of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia/nigrescens, Peptostreptococcus micros, Bacteroides forsythus, and Campylobacter rectus. Subjects with Cohen syndrome had alveolar bone loss more frequently and the bone loss was more extensive (Mann-Whitney U-test: P < 0.05) than in the controls. They also harbored one or several of the putative periodontal pathogens (Mann-Whitney U-test: P < 0.001) more often than the controls. We conclude that subjects with Cohen syndrome have increased susceptibility to early periodontal breakdown which is likely to be associated with...Continue Reading

References

Feb 1, 1978·Journal of Clinical Periodontology·P A Reichart, H Dornow
Jun 1, 1989·Journal of Periodontology·A CarrassiG Vogel
Aug 1, 1969·Oral Surgery, Oral Medicine, and Oral Pathology·K W Davey, P A Konchak
Mar 1, 1983·Journal of Clinical Periodontology·H N Newman, D C Rule
Mar 1, 1983·Journal of Clinical Periodontology·P C BaehniG Cimasoni
May 1, 1980·Pediatric Clinics of North America·R M Weetman, L A Boxer
Jun 1, 1994·Nature Genetics·E TahvanainenA de la Chapelle
Jun 1, 1993·Journal of Periodontology·V KirstiläJ Laine

❮ Previous
Next ❯

Citations

Aug 15, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·F-Y DengH-W Deng
Jul 29, 2005·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Tuong-Nam NguyenRobert K Koenekoop
Aug 31, 2000·Ophthalmology·S Kivitie-KallioR Norio
Jun 6, 2003·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Carlos García-BallestaLuis Alberto Bravo-González
Sep 1, 2005·Journal of Clinical Periodontology·Lior ShapiraDenis F Kinane
Apr 20, 2011·Periodontology 2000·Avula Haritha, Avula Jayakumar
Apr 21, 2010·Periodontology 2000·Gary C Armitage, Mary P Cullinan
Apr 18, 2014·Periodontology 2000·Ahmed Khocht, Jasim M Albandar
Nov 27, 1998·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·P ArvioS Pirinen
Jun 28, 2005·Dental Clinics of North America·Dimitris N Tatakis, Purnima S Kumar
May 3, 2003·Atlas of the Oral and Maxillofacial Surgery Clinics of North America·Dean K WhiteJason E Ford
Jun 23, 2000·Annals of Periodontology·D F Kinane
Jul 31, 2003·Journal of Periodontology·Başak DoğanSirkka Asikainen
Jul 31, 2001·American Journal of Medical Genetics·S Kivitie-Kallio, R Norio
Apr 23, 2015·Journal of Dental Research·N M MoutsopoulosG Hajishengallis
Jan 14, 2004·Periodontology 2000·Gary C Armitage
Jul 18, 2002·European Journal of Oral Sciences·Laura LakioSirkka Asikainen
Mar 29, 2007·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Chrisovalantou CheretakisMichael Glogauer
Jan 10, 2006·Periodontology 2000·Denis F KinanePanagiota G Stathopoulou
Oct 9, 2009·International Reviews of Immunology·Nima RezaeiChristoph Klein
Jul 17, 2001·Periodontology 2000·P Hodge, B Michalowicz
Jan 8, 2004·Critical Reviews in Clinical Laboratory Sciences·Jeffrey E MingJohn M Graham
Aug 9, 2003·Acta Anaesthesiologica Scandinavica·S Orbach-ZingerM Perouansky
Mar 14, 2013·Dental Update·Ashish KumarMandeep Singh Virdi
Nov 18, 2020·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Arnaud LafonLaurent Laforest
Jul 17, 2021·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Heliya ZiaeiNima Rezaei

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.