Periodontal inflammatory burden correlates with C-reactive protein serum level

Acta Odontologica Scandinavica
Eva SkalericUros Skaleric

Abstract

The aim of study was to present a new method for evaluation of the periodontal inflammatory burden, to apply the method to the adult population and to correlate it with serum levels of C-reactive protein (CRP). On 515 extracted teeth was measured the neck circumferences (NC). The average values of the NC were obtained for 16 male and 16 female individual tooth types. In the clinical part of this study 238 dentate subjects were included. The subgingival area, inflamed area and periodontal wound size were calculated from NC, probing depth and BOP. The sum of the inflamed and ulcerated subgingival areas of all teeth represented the total periodontal inflammatory burden of an individual. Serum levels of CRP were measured by immunochemical method. The average subgingival area in 238 subjects was calculated to be 13.11 ± 6.35 cm(2) and inflammatory burden area 9.25 ± 5.57 cm(2). The periodontal bleeding wound (p < 0.05) was significantly larger in men. The increased serum levels of CRP correlated with periodontal inflammatory burden (p < 0.05). This new method quantifies the inflammatory burden caused by periodontal disease. The size of the inflammatory burden is correlated with increased serum levels of CRP.

References

May 1, 1992·Oral Surgery, Oral Medicine, and Oral Pathology·F M LucartortoJ Maza
Oct 1, 1991·Journal of Periodontology·J E LofthusS Nachnani
Dec 1, 1989·Community Dentistry and Oral Epidemiology·U Skaleric, M Kovac-Kavcic
Jun 1, 1995·International Journal of Oral and Maxillofacial Surgery·K OkabeE Yamamoto
Jun 1, 1995·Endodontics & Dental Traumatology·G J DebelianL Tronstad
Apr 1, 1994·Journal of Clinical Periodontology·P P Hujoel
Apr 3, 1997·The New England Journal of Medicine·P M RidkerC H Hennekens
Feb 26, 2000·Journal of Dental Research·G D SladeJ S Pankow
Mar 15, 2001·Journal of Periodontal Research·P P HujoelM A Listgarten
Oct 2, 2001·Journal of Periodontology·B NoackE De Nardin
Feb 16, 2002·Journal of Periodontology·Sabine O GeertsEric H Rompen
Mar 6, 2002·Circulation·Peter LibbyAttilio Maseri
Mar 13, 2002·Circulation·Johann W AuerBernd Eber
Jul 10, 2002·Periodontology 2000·Jasim M Albandar
Oct 9, 2002·Journal of Internal Medicine·G J Blake, P M Ridker
Apr 30, 2003·Diabetes Care·Dana E KingWilliam S Pearson
May 10, 2003·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Sok-Ja JanketJudith A Jones
Feb 20, 2004·Annals of Periodontology·Frank A ScannapiecoSusanna Paju
Jul 17, 2004·Stroke; a Journal of Cerebral Circulation·Moïse DesvarieuxThomas Kocher
Oct 1, 2004·Journal of Periodontology·Yousef S KhaderMousa A Alomari
Dec 24, 2004·Diabetes Care·Aramesh SaremiWilliam C Knowler
Jun 25, 2005·Journal of Periodontology·Yousef S Khader, Quteish Ta'ani
Aug 17, 2005·Journal of Periodontology·Brian Burt, UNKNOWN Research, Science and Therapy Committee of the American Academy of Periodontology
Nov 9, 2005·Journal of Periodontology·Khalaf F Al-ShammariHom-Lay Wang
Jan 4, 2006·Journal of Diabetes and Its Complications·Yousef S KhaderWalid Q Batayha
Jun 1, 2006·Journal of Periodontology·Trang N SalzbergHarvey A Schenkein
Sep 14, 2007·Journal of Clinical Periodontology·Gloria Inés LafauriePaola Andrea Hurtado
Dec 7, 2007·The American Journal of Medicine·Ravi DhingraChristopher J O'Donnell
Feb 26, 2008·Journal of Clinical Periodontology·Spiros ParaskevasBruno G Loos
Jun 12, 2008·Journal of Periodontal Research·K A JandikA Progulske-Fox
Jun 20, 2008·Journal of Clinical Periodontology·Willem NesseArjan Vissink

❮ Previous
Next ❯

Citations

Oct 16, 2016·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Gediminas ŽekonisJulija Narbutaitė

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.