Periodontal regeneration with or without limited orthodontics for the treatment of 2- or 3-wall infrabony defects

Journal of Periodontology
Shigeki Ogihara, Hom-Lay Wang

Abstract

Limited orthodontics are shown to be effective in the correction of infrabony defects. Studies have also demonstrated the efficacy of using enamel matrix derivative (EMD) with demineralized freeze-dried bone allograft (DFDBA) to treat infrabony defects. This study aims to compare the clinical efficacy of limited orthodontics combined with EMD/DFDBA in the treatment of 2- or 3-wall infrabony defects. A randomized, parallel clinical trial was conducted in a private periodontal practice (Tokyo, Japan) between April 2004 and October 2008. Treatment period was 1 year with a 1-year follow-up. Forty-seven randomized patients, mean age of 53 ± 10.7 years, were allocated into two intervention groups: ortho/EMD/DFDBA (n = 24) and EMD/DFDBA (n = 23). Each patient had either a 2- or 3-wall infrabony defect of ≥6 mm deep. Probing depth and clinical attachment level were measured at baseline and 1 year. The primary outcome measure was absolute change in probing depth and clinical attachment level from baseline to 1-year follow-up. The secondary outcome measure was absolute change in open probing attachment level gain and percentage defect resolution from baseline to 6-month reentry surgery. Infrabony defects were surgically treated with EMD ...Continue Reading

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Citations

May 3, 2014·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·Yijia XieShuliang Yang
Feb 24, 2016·International Journal of Dentistry·Angelina GorbunkovaGiulio Rasperini
Sep 5, 2015·The Journal of Evidence-based Dental Practice·Francesco Cairo, Umberto Pagliaro
Mar 30, 2016·Progress in Polymer Science·Fa-Ming Chen, Xiaohua Liu
Sep 13, 2014·Journal of Periodontology·Richard T KaoMark A Reynolds
Apr 21, 2016·Clinical and Experimental Dental Research·Egle ZasciurinskieneKrister Bjerklin

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